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. 2022 Nov 17;2022(11):CD014963. doi: 10.1002/14651858.CD014963.pub2

Comparison 2. Subgroup analysis: respiratory support for the comparison of corticosteroids plus standard care versus standard care (plus/minus placebo) for hospitalised individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 All‐cause mortality up to 30 days 4 7137 Risk Ratio (M‐H, Random, 95% CI) 0.91 [0.81, 1.03]
2.1.1 No oxygen 1 1535 Risk Ratio (M‐H, Random, 95% CI) 1.27 [1.00, 1.61]
2.1.2 Low‐flow oxygen only 2 85 Risk Ratio (M‐H, Random, 95% CI) 0.90 [0.50, 1.63]
2.1.3 NIV, high‐flow, and low‐flow oxygen combined 1 3883 Risk Ratio (M‐H, Random, 95% CI) 0.89 [0.79, 1.00]
2.1.4 NIV or high‐flow oxygen only 2 195 Risk Ratio (M‐H, Random, 95% CI) 0.91 [0.53, 1.58]
2.1.5 Invasive ventilation 3 1439 Risk Ratio (M‐H, Random, 95% CI) 0.85 [0.70, 1.04]