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. 2022 Nov 17;2022(11):CD014963. doi: 10.1002/14651858.CD014963.pub2

Comparison 11. Subgroup analysis: < 70 years versus ≥ 70 years for the comparison of high‐dose dexamethasone (12 mg or higher) versus low‐dose dexamethasone (6 mg to 8mg) for hospitalised individuals with a confirmed diagnosis of symptomatic COVID‐19.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
11.1 All‐cause mortality up to 30 days 2 1069 Risk Ratio (M‐H, Random, 95% CI) 0.87 [0.73, 1.04]
11.1.1 <70 years 2 707 Risk Ratio (M‐H, Random, 95% CI) 0.82 [0.63, 1.07]
11.1.2 ≥ 70 years 2 362 Risk Ratio (M‐H, Random, 95% CI) 0.91 [0.73, 1.15]
11.2 All‐cause mortality up to 120 days 2 1066 Risk Ratio (M‐H, Random, 95% CI) 0.88 [0.76, 1.03]
11.2.1 <70 years 2 706 Risk Ratio (M‐H, Random, 95% CI) 0.80 [0.63, 1.02]
11.2.2 ≥ 70 years 2 360 Risk Ratio (M‐H, Random, 95% CI) 0.94 [0.78, 1.14]