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. 2022 Nov 17;2022(11):CD014963. doi: 10.1002/14651858.CD014963.pub2

IRCT20200611047727N3.

Methods Trial design: single‐blinded, RCT
Sample size: 60
Setting: inpatient
Language: English
Number of centres: 1
Type of intervention (treatment/prevention): treatment
Participants Inclusion criteria
  • Oxygen saturation level < 93

  • At least 7 days have passed since the onset of symptoms

  • At least 5 days of antiviral treatment


Exclusion criteria
  • Patients who are unable to go for follow‐up scans

Interventions Details of intervention:
  • Type of corticosteroids: methylprednisolone

  • Dose: 0.75 to 1 mg/kg for 5 days

  • Route of administration: IV


Treatment details of control group (e.g. dose, route of administration): standard care
Concomitant therapy: no
Outcomes Primary study outcome: radiological changes (before the intervention and 6 weeks later)
Notes Recruitment status: completed
Prospective completion date: no information
Date last update was posted: 3 January 2021
Sponsor/funding: Shahid Beheshti University of Medical Sciences