TABLE 1.
Losses and gainsa of CMI responses to B. pertussis antigens in 48-month-old pertussis vaccine recipients
| Antigen | Loss of CMI+ (%)
|
Gain of CMI+ (%)
|
||
|---|---|---|---|---|
| aP-CB | aP-SB | aP-CB | aP-SB | |
| PT | 33 | 20 | 65.2 | 55.5 |
| PRN | 28 | 22 | 50 | 69.2 |
| FHA | 30 | 37.5 | 54.4 | 36.4 |
a
Calculated with respect to the proliferative PBMC responses of the same subjects at 7 months of age. CMI was defined as positive (CMI+) when the difference between the lymphoproliferative response (measured as [3H]thymidine incorporation and expressed in counts per minute) of the antigen-stimulated PBMC culture and that of the unstimulated control culture was ≥3,000 (corresponding to a stimulation index of ≥4).