Table 6.
Cartilage damage change – any MOAKS worsening (baseline to 24 months)
| N = 226 | All knees | No ROA | ROA | P-value | |||||
|---|---|---|---|---|---|---|---|---|---|
| Frequency | Percent | Frequency | Percent | Frequency | Percent | ||||
| Worsening—total MOAKS cartilage score (only full-grade worsening) | |||||||||
| Knee | None vs. any | 0 | 106 | 46.9 | 69 | 63.3 | 37 | 31.6 | 0.0000 |
| ≥ 1 | 120 | 53.1 | 43 | 36.7 | 80 | 68.4 | |||
| Number of regions | 1 | 60 | 26.5 | 26 | 23.9 | 34 | 29.1 | ||
| 2 | 35 | 15.5 | 9 | 8.3 | 26 | 22.2 | |||
| 3 | 17 | 7.5 | 3 | 2.8 | 14 | 12.0 | |||
| 4 | 6 | 2.7 | 2 | 1.8 | 4 | 3.4 | |||
| 5 | 2 | 0.9 | 0 | 0.0 | 2 | 1.7 | |||
| MFTJ | None vs. any | 0 | 172 | 76.1 | 96 | 88.1 | 76 | 65.0 | 0.0000 |
| ≥ 1 | 54 | 23.9 | 13 | 11.9 | 41 | 35.0 | |||
| Number of regions | 1 | 40 | 17.7 | 11 | 10.1 | 29 | 24.8 | ||
| 2 | 12 | 5.3 | 1 | 0.9 | 11 | 9.4 | |||
| 3 | 2 | 0.9 | 1 | 0.9 | 1 | 0.9 | |||
| LFTJ | None vs. any | 0 | 176 | 77.9 | 99 | 90.8 | 77 | 65.8 | 0.0000 |
| ≥ 1 | 50 | 22.1 | 10 | 9.2 | 40 | 34.2 | |||
| Number of regions | 1 | 35 | 15.5 | 8 | 7.3 | 27 | 23.1 | ||
| 2 | 11 | 4.9 | 2 | 1.8 | 9 | 7.7 | |||
| 3 | 3 | 1.3 | 0 | 0.0 | 3 | 2.6 | |||
| 4 | 1 | 0.4 | 0 | 0.0 | 1 | 0.9 | |||
| PFJ | None vs. any | 0 | 168 | 74.3 | 83 | 76.1 | 85 | 72.6 | 0.5176 |
| ≥ 1 | 58 | 25.7 | 26 | 23.9 | 32 | 27.4 | |||
| Number of regions | 1 | 43 | 19.0 | 20 | 18.3 | 23 | 19.7 | ||
| 2 | 13 | 5.8 | 5 | 4.6 | 8 | 6.8 | |||
| 3 | 2 | 0.9 | 1 | 0.9 | 1 | 0.9 | |||
| Worsening—total score including within-grade worsening | |||||||||
| Knee | None vs. any | 0 | 85 | 37.6 | 61 | 56.0 | 24 | 20.5 | 0.0000 |
| ≥ 1 | 141 | 73.9 | 48 | 44.0 | 93 | 79.5 | |||
| Number of regions | 1 | 59 | 26.1 | 30 | 27.5 | 29 | 24.8 | ||
| 2 | 43 | 19.0 | 12 | 11.0 | 31 | 26.5 | |||
| 3 | 29 | 12.8 | 4 | 3.7 | 25 | 21.4 | |||
| 4 | 7 | 3.1 | 2 | 1.8 | 5 | 4.3 | |||
| 5 | 3 | 1.3 | 0 | 0.0 | 3 | 2.6 | |||
| MFTJ | None vs. any | 0 | 154 | 68.1 | 93 | 85.3 | 61 | 52.1 | 0.0000 |
| ≥ 1 | 72 | 31.9 | 16 | 14.7 | 56 | 47.9 | |||
| Number of regions | 1 | 50 | 22.1 | 13 | 11.9 | 37 | 31.6 | ||
| 2 | 16 | 7.1 | 2 | 1.8 | 14 | 12.0 | |||
| 3 | 6 | 2.7 | 1 | 0.9 | 5 | 4.3 | |||
| LFTJ | None vs. any | 0 | 168 | 74.3 | 97 | 89.0 | 71 | 60.7 | 0.0000 |
| ≥ 1 | 58 | 25.7 | 12 | 11.0 | 46 | 39.3 | |||
| Number of regions | 1 | 38 | 16.8 | 10 | 9.2 | 28 | 23.9 | ||
| 2 | 16 | 7.1 | 2 | 1.8 | 14 | 12.0 | |||
| 3 | 3 | 1.3 | 0 | 0.0 | 3 | 2.6 | |||
| 4 | 1 | 0.4 | 0 | 0.0 | 1 | 0.9 | |||
| PFJ | None vs. any | 0 | 154 | 68.1 | 77 | 70.6 | 77 | 65.8 | 0.3948 |
| ≥ 1 | 72 | 31.9 | 32 | 29.4 | 40 | 34.2 | |||
| Number of regions | 1 | 54 | 23.9 | 25 | 22.9 | 29 | 24.8 | ||
| 2 | 16 | 7.1 | 6 | 5.5 | 10 | 8.5 | |||
| 3 | 2 | 0.9 | 1 | 0.9 | 1 | 0.9 | |||