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. 2022 Nov 17;23:990. doi: 10.1186/s12891-022-05964-9

Table 2.

Diabetes-related characteristics between group 1 and group 2 at the first-stage revision arthroplasty

Variables Group 1: HbA1c < 7 (n = 44) Group 2: HbA1c ≥ 7 (n = 44) p
Diabetes subtype
  Type 1 0 (0%) 0 (0%) 1
  Type 2 44 (100%) 44 (100%)
  Duration of Diabetes, years (SD) 9.59 (5.50) 11.5 (5.52) 0.3
  Fasting glucose, mmol/l (SD) 152 (60.2) 300 (145)  < 0.001*
  HbA1c (1st stage), % (SD) 6.26 (0.539) 10.1 (1.68)  < 0.001*
  HbA1c (last stage), % (SD) 6.32 (0.342) 6.86 (1.10) 0.116
  Self-reported drug intake (N, %) 5.00 (22.7%) 9.00 (40.9%) 0.332
  No glucose-lowering drugs 2 (4.5%) 4 (9.1%) 1
Anti-diabetic agent
  Metformin 18 (40.9%) 26 (59.1%) 0.366
  GLP-1 receptor agonist (Liraglutide, dulaglutide, soliqua) 0 (0%) 2 (4.5%) 1
  SGLT2 inhibitor (Empagliflozin, dapagliflozin, canagliflozin) 0 (0%) 2 (4.5%) 1
  Sulfonylurea (Glipizide, Glimepiride, Gliclazide) 8 (18.2%) 24 (54.5%) 0.0268*
  Glinides (Mitiglinde, Repaglinide, Nateglinide) 0 (0%) 2 (4.5%) 1
  TZD (Pioglitazone, Rosiglitazone) 2 (4.5%) 2 (4.5%) 1
  DPP4 inhibitor (Saxagliptin, Linagliptin, Alogliptin, Vildagliptin) 2 (4.5%) 18 (40.9%) 0.00934*
  Acarbose 0 (0%) 12 (27.3%) 0.0211
  Insulin only 0 (0%) 8 (18.2%) 0.108
  Insulin combined with other OAD 4 (9.1%) 20 (45.5%) 0.0157*
  ACE inhibitor or ARB 4 (9.1%) 20 (45.5%) 0.0157*
  Diuretic 8 (18.2%) 10 (22.7%) 1
  Calcium antagonist 16 (36.4%) 20 (45.5%) 0.759
  Beta blocker 10 (22.7%) 20 (45.5%) 0.203
  Other antihypertensive drug 14 (31.8%) 14 (31.8%) 1
  Any antihypertensive drug 10 (22.7%) 8 (18.2%) 1
  Statin 12 (27.3%) 10 (22.7%) 1
  Fibrate 0 (0%) 0 (0%) 1
  Antiplatelet therapy 0 (0%) 4 (9.1%) 0.488
  Anti-coagulant 10 (22.7%) 12 (27.3%) 1

HbA1c glycohemoglobin, SD standard deviation, GLP-1 Glucagon-like peptide-1, SGLT2 sodium-glucose cotransporter 2, TZD thiazolidinedione, DPP4 Dipeptidyl peptidase 4, OAD oral anti-diabetic drug, ACE angiotensin-converting enzyme, ARB angiotensin II receptor blockers

*p value < 0.05