Table 1.
Patient Demographics for group 1, 2, and 3
| N reported | Group 1 (N = 12) | Group 2 (N = 37) | Group 3 (N = 26) | Combined | P-value | |
|---|---|---|---|---|---|---|
| Age | 74 | 63.0 (58.2–68.2) | 64.0 (58.0–68.0) | 63.0 (59.0–69.0) | 63.0 (58.2–69.0) | 0.921 |
| Gender | 75 | 0.939 | ||||
| Female | 3 (25%) | 10 (27%) | 6 (23%) | 19 (25%) | ||
| Male | 9 (75%) | 27 (73%) | 20 (77%) | 56 (75%) | ||
| Race | 75 | 0.735 | ||||
| American Indian /Alaska | 0 (0%) | 1 (3%) | 0 (0%) | 1 (1%) | ||
| Asian | 0 (0%) | 2 (5%) | 1 (4%) | 3 (4%) | ||
| Black | 0 (0%) | 4 (11%) | 4 (15%) | 8 (11%) | ||
| Native Hawaiian | 0 (0%) | 1 (3%) | 0 (0%) | 1 (1%) | ||
| Other | 0 (0%) | 1 (3%) | 1 (4%) | 2 (3%) | ||
| Unknown | 2 (17%) | 1 (3%) | 1 (4%) | 4 (5%) | ||
| White | 10 (83%) | 27 (73%) | 19 (73%) | 56 (75%) | ||
| Ethnicity | 75 | 0.499 | ||||
| Hispanic or Latino | 1 (8%) | 1 (3%) | 2 (8%) | 4 (5%) | ||
| Non-Hispanic | 9 (75%) | 34 (92%) | 22 (85%) | 65 (87%) | ||
| Unknown | 2 (17%) | 2 (5%) | 1 (4%) | 5 (7%) | ||
| Other | 0 (0%) | 0 (0%) | 1 (4%) | 1 (1%) | ||
| Causes of Cirrhosis | ||||||
| Alcohol | 75 | 0.094 | ||||
| Yes | 2 (17%) | 11 (30%) | 2 (8%) | 15 (20%) | ||
| No | 10 (83%) | 26 (70%) | 24 (92%) | 60 (80%) | ||
| Hepatitis B | 75 | 0.508 | ||||
| Yes | 0 (0%) | 3 (8%) | 1 (4%) | 4 (5%) | ||
| No | 12 (100%) | 34 (92%) | 25 (96%) | 71 (95%) | ||
| Hepatitis C | 75 | 0.869 | ||||
| Yes | 5 (42%) | 15 (41%) | 9 (35%) | 29 (39%) | ||
| No | 7 (58%) | 22 (59%) | 17 (65%) | 46 (61%) | ||
| NASH | 75 | 0.011 | ||||
| Yes | 4 (33%) | 1 (3%) | 3 (12%) | 8 (11%) | ||
| No | 8 (67%) | 36 (97%) | 23 (88%) | 67 (89%) | ||
| Other | 75 | 0.908 | ||||
| Yes | 1 (8%) | 2 (5%) | 2 (8%) | 5 (7%) | ||
| No | 11 (92%) | 36 (97%) | 23 (88%) | 67 (89%) | ||
| Bilirubin | 74 | 0.800 (0.675–0.925) | 1.05 (0.600–1.625) | 0.700 (0.500–0.900) | 0.800 (0.600–1.300) | 0.023 |
| Albumin | 74 | 3.60 (3.18–3.92) | 3.50 (3.20–3.68) | 3.35 (3.08–3.60) | 3.50 (3.10–3.70) | 0.324 |
| Ascites | 75 | 0.014 | ||||
| Yes | 2 (17%) | 16 (43%) | 3 (12%) | 21 (28%) | ||
| No | 10 (83%) | 21 (57%) | 23 (88%) | 54 (72%) | ||
| Hepatic Encephalopathy | 75 | 0.333 | ||||
| Yes | 1 (8%) | 1 (3%) | 0 (0%) | 2 (3%) | ||
| No | 11 (92%) | 36 (97%) | 26 (100%) | 73 (97%) | ||
| MELD | 70 | 8.0 (7.0–9.5) | 10.0 (8.0–12.0) | 7.0 (6.0–9.0) | 9.0 (7.0–11.0) | < 0.001 |
| Child Pugh Class | 70 | < 0.001 | ||||
| Class A | 12 (100%) | 14 (39%) | 18 (82%) | 44 (63%) | ||
| Class B/C | 0 (0%) | 22 (61%) | 4 (18%) | 26 (37%) | ||