Table 2.
Univariate and multivariate Cox regression analyses
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| T stage | 539 | ||||
| T1&T2 | 349 | Reference | |||
| T3&T4 | 190 | 3.228 (2.382–4.374) | < 0.001 | 2.055 (1.300-3.250) | 0.002 |
| N stage | 257 | ||||
| N0 | 241 | Reference | |||
| N1 | 16 | 3.453 (1.832–6.508) | < 0.001 | 1.602 (0.815–3.148) | 0.171 |
| M stage | 506 | ||||
| M0 | 428 | Reference | |||
| M1 | 78 | 4.389 (3.212–5.999) | < 0.001 | 3.089 (1.922–4.963) | < 0.001 |
| Gender | 539 | ||||
| Female | 186 | Reference | |||
| Male | 353 | 0.930 (0.682–1.268) | 0.648 | ||
| Age | 539 | ||||
| ≤ 60 | 269 | Reference | |||
| > 60 | 270 | 1.765 (1.298–2.398) | < 0.001 | 1.858 (1.216–2.840) | 0.004 |
| CX3CL1 | 539 | 0.688 (0.609–0.776) | < 0.001 | 0.682 (0.562–0.826) | < 0.001 |