Table 4.
Tribe-wise phenotype distribution and allele frequency of HbS and α-thalassaemia among the unrelated 13 PVTGs of Odisha
| PVTG Tribe | AA | AS | SS | HbS | χ2 | αα/αα | αα/–α | –α/–α | Hbα | χ2 |
|---|---|---|---|---|---|---|---|---|---|---|
| Juang | 64 | 2 | 0 | 0.015 | 0.0156 | ND | ND | ND | ||
| Kutia Kondho | 96 | 1 | 0 | 0.005 | 0.0026 | ND | ND | ND | ||
| Paudi Bhuyan | 202 | 6 | 1 | 0.019 | 11.57* | 205 | 6 | 0 | 0.0142 | 0.0439 |
| Dongoria Kondho | 115 | 2 | 0 | 0.009 | 0.008 | 115 | 2 | 0 | 0.0085 | 0.0087 |
| Langia Saora | 117 | 10 | 0 | 0.039 | 0.213 | 120 | 7 | 0 | 0.0276 | 0.102 |
| Didayi | 67 | 6 | 0 | 0.041 | 0.134 | 70 | 3 | 0 | 0.0205 | 0.0321 |
| Saora | 139 | 13 | 0 | 0.042 | 0.303 | 146 | 5 | 1 | 0.023 | 10.989* |
AA normal individual; AS sickle cell heterozygote; SS sickle cell homozygote; HbS sickle cell allele; χ2 chi square value; αα/αα normal α gene; αα/–α α gene single gene deletion; -α/–α α double gene deletion; Hbα allele frequency of α gene deletion; ND not detected
*Statistically significant (p < 0.05)