Table 1.
aPulmonary function test results before and after treatment with immunosuppression
| Before Treatment | After 9 months of Treatment | After 3 years of Treatment | |
|---|---|---|---|
| FVC | 3.8 L (94% ref) | 4.9 L (117% ref) | 5.6 L (118% ref) |
| FEV1 | 2.8 L (80% ref) | 3.6 L (99% ref) | 4.1 L (100% ref) |
| FEV1/FVC ratio | 73% | 73% | 73% |
| FEF25–75 | 2.2 L/s (56% ref) | 2.8 L/s (71% ref) | 3.3 L/s (72% ref) |
| TLC | 5.8 L (120% ref) | 6.5 L (129% ref) | 7.6 L (142% ref) |
| RV | 1.9 L (193% ref) | 1.6 L (154% ref) | 1.9 L (176% ref) |
| RV/TLC ratio | 33% | 25% | 26% |
| DLCO | 26.2 mL/mmHg/min (81% ref) | 28.8 mL/mmHg/min (88% ref) | 33.5 mL/mmHg/min (87% ref) |
| Interpretation | |||
| Spirometry | Mild-moderate obstructive pattern | Mild obstructive pattern | Mild obstructive pattern |
| Lung volumes | TLC, RV and RV/TLC elevated | TLC and RV elevated | TLC and RV elevated |
| DLCO | Normal | Normal (improved from previous) | Normal (improved from previous) |
aAbbreviations: FVC forced vital capacity, FEV1 forced expiratory volume in 1 second, FEF25–75 forced expiratory flow at 25–75% of FVC, TLC total lung capacity, RV residual volume, DLCO diffusing capacity for carbon monoxide, L liters, s second, ref reference, mL/mmHg/min milliliters/millimeters of mercury/minute