Table 2.

Mortality rate of BTC overall and by anatomic sites by race/ethnicity, ASR: 2001–2015 [27, 28]

A)	ASR (95% CI)			B)	ASR (95% CI)
	BTC (N = 117,854)	ICC (N = 64,882)	GBC (N = 30,521)		ECC (N = 9889)	AVC (N = 4774)	Overlapping & NOS (N = 2626)
All races/ ethnicities	3.40 (3.38 to 3.42)	1.87 (1.85 to 1.88)	0.88 (0.87 to 0.89)	All races/ ethnicities	1.10 (1.08 to 1.12)	0.53 (0.52 to 0.55)	0.29 (0.28 to 0.30)
White	3.25 (3.23 to 3.28)	1.82 (1.80 to 1.84)	0.78 (0.77 to 0.79)	White	1.00 (0.98 to 1.03)	0.48 (0.47 to 0.50)	0.27 (0.26 to 0.28)
Hispanic	4.43 (4.34 to 4.52)	2.26 (2.20 to 2.33)	1.47 (1.42 to 1.52)	Hispanic	1.46 (1.38 to 1.55)	0.80 (0.74 to 0.87)	0.42 (0.38 to 0.47)
Black	3.48 (3.41 to 3.55)	1.71 (1.66 to 1.75)	1.21 (1.18 to 1.25)	Black	0.99 (0.92 to 1.06)	0.51 (0.46 to 0.56)	0.28 (0.24 to 0.32)
American Indian/Alaska Native	3.97 (3.69 to 4.25)	1.93 (1.74 to 2.13)	1.45 (1.28 to 1.63)	American Indian/Alaska Native	1.19 (0.94 to 1.48)	0.48 (0.32 to 0.67)	0.25 (0.14 to 0.40)
Asian/Pacific Islander	4.30 (4.18 to 4.42)	2.57 (2.48 to 2.66)	1.02 (0.96 to 1.08)	Asian/Pacific Islander	1.60 (1.51 to 1.69)	0.64 (0.58 to 0.70)	0.31 (0.27 to 0.35)

Mortality rates are age-standardized and reported as deaths per 100,000 person-years. A) Mortality rates for total BTC, ICC and GBC, evaluated using NPCR-SEER data. Total BTC rates from the NPCR-SEER database includes ICC, GBC, and Other Biliary Cancers. B) ECC, AVC and Overlapping & NOS mortality data, evaluated using the SEER 18 Incidence-based mortality database

ASR Age-standardized rate, BTC Biliary tract cancer, CI Confidence interval, GBC Gallbladder cancer, ICC Intrahepatic cholangiocarcinoma, SEER Surveillance, Epidemiology, and End Results