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. 2022 Nov 3;7(45):40659–40681. doi: 10.1021/acsomega.2c05307

Figure 4.

Figure 4

(A) Scatter plot of DprE1 pIC50 (−log10[IC50 (molar)]) versus pMIC (−log10[MIC (molar)]) against Mtb for covalent (left) and noncovalent (right) inhibitors and Pearson correlation coefficient between DprE1 pIC50 and pMIC. (B) Scatter plot of cytotoxicity pCC50 (−log10[CC50 (molar)]) versus pMIC for covalent (left) and noncovalent (right) inhibitors and Pearson correlation coefficient between pCC50 and pMIC.