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. Author manuscript; available in PMC: 2022 Nov 17.

Published in final edited form as: J Heart Lung Transplant. 2022 Apr 10;41(7):919–927. doi: 10.1016/j.healun.2022.04.002

(A) Histogram of dd-cfDNA fraction (%) in nonrejection biopsy matched samples (n = 762). (B) dd-cfDNA fraction (%) in non-AR samples over time. dd-cfDNA fraction >24 months post-transplant was significantly higher than dd-cfDNA fraction for all other time periods combined. Med refers to median dd-cfDNA fraction (%). For both 4A and 4B, the red dashed lines represent the 0.15% dd-cfDNA cutoff.

(A) Histogram of dd-cfDNA fraction (%) in nonrejection biopsy matched samples (n = 762). (B) dd-cfDNA fraction (%) in non-AR samples over time. dd-cfDNA fraction >24 months post-transplant was significantly higher than dd-cfDNA fraction for all other time periods combined. Med refers to median dd-cfDNA fraction (%). For both 4A and 4B, the red dashed lines represent the 0.15% dd-cfDNA cutoff.