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. Author manuscript; available in PMC: 2022 Nov 17.

Published in final edited form as: J Heart Lung Transplant. 2022 Apr 10;41(7):919–927. doi: 10.1016/j.healun.2022.04.002

Table 3.

Performance of dd-cfDNA Fraction in Discriminating AR From Nonrejection for the Study Cohort

Measure	dd-cfDNA fraction (%) cutoff
Measure	0.12	0.15	0.20

Sensitivity	86.59% (71.98%–100%)	78.52% (60.73%–96.30%)	78.58% (60.80%–96.35%)
Specificity	72.03% (65.86%–78.20%)	76.88% (71.08%–82.67%)	82.12% (76.86%–87.39%)
PPV	23.42% (18.44%– 28.40%)	25.12% (18.76%–31.47%)	30.27% (22.43%–38.11%)
NPV	98.19% (96.26%–100%)	97.31% (95.14%–99.49%)	97.49% (95.45%–99.53%)
AUC-ROC		0.86 (0.77–0.96)

Brackets show 95% confidence limits.