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. 2022 Oct 25;55(22):3205–3217. doi: 10.1021/acs.accounts.2c00521

Figure 5.

Figure 5

Controlling the spatiotemporal aspects of the lipid probes. (A) Lipids can be functionalized with either a photocleavable cage (cg-2-AG) or a photoswitchable azobenzene (cis-AzCA4). Upon irradiation, the probe is converted to its active form to exert its biological function. (B) Spatial control over lipid release can be achieved through caged-lipid strategies with either targeted irradiation or a subcellularly targeted cage.