Table 1. Characteristics of ESBL-producing E. coli.

Strains	Month	Site	Phylogroupa	Beta-actamasesb	Integrons/transposonsc	Plasmid Replicond	Antibiotic resistance patternse
EH2101	Dec-20	Kok River	A	CTX-M-15	ISEcp1	F, FIB, I1-Iγ, K, B/O	40
EH2102	Dec-20	Kok River	B2	CTX-M-15	Int1	F, FIA, I1-Iγ	11
EH3101	Dec-20	Kok River	D	CTX-M-15	ISEcp1	F	24
EH1201	Jan-21	Kok River	B1	CTX-M-14	ISEcp1	F, FIB, I1-Iγ, FIIAs, X	13
EH1203	Jan-21	Kok River	B1	CTX-M-15	-	F, FIB, I1-Iγ, Y, K, B/O	59
EH2201	Jan-21	Kok River	B2	CTX-M-27	Int1	F, FIA, I1-Iγ	29
EH2204	Jan-21	Kok River	A	CTX-M-14	-	F, HI1, K	63
EH3201	Jan-21	Kok River	B1	CTX-M-15	-	F, I1-Iγ, K, B/O	50
EH1303	Feb-21	Kok River	B1	CTX-M-15	ISEcp1	F, FIA, Y, K	49
EH1306	Feb-21	Kok River	B1	CTX-M-14	Int1, ISEcp1	F, FIB, HI2, K	21
EH1307	Feb-21	Kok River	C	CTX-M-14	Tn3, ISEcp1	F, FIB, I1-Iγ, A/C, B/O, FIIAs	13
EH2301	Feb-21	Kok River	A	CTX-M-55, TEM-1	Int1, Tn3, ISEcp1	F, HI2, X	7
EH3301	Feb-21	Kok River	A	CTX-M-15	-	F, Y, K, B/O	51
EH3302	Feb-21	Kok River	A	CTX-M-14	Tn3	F, FIB, Y	39
EH1401	Mar-21	Kok River	B1	CTX-M-15, TEM-1	Int1, Tn3, ISEcp1	–	18
EH1402	Mar-21	Kok River	A	CTX-M-55	Int1	F, FIB, HI1	1
H2404	Mar-21	Kok River	B1	CTX-M-15	ISEcp1	F, FIB, HI1, I1-Iγ	32
EH2401	Mar-21	Kok River	B2	CTX-M-15	Int1	F, FIA, I1-Iγ	8
EH2402	Mar-21	Kok River	B1	CTX-M-55, TEM-1	Int1, Tn3, ISEcp1	F, FIB, I1-Iγ	4
EH6303	May-21	Kok River	D	CTX-M-15	-	F, I1-Iγ, B/O	58
EH8203	Jul-21	Kok River	D	CTX-M-15, TEM-1	Int1, Int2, ISEcp1	F, HI2, K	2
EH9101	Aug-21	Kok River	D	CTX-M-15, TEM-1	Int1, Int2, ISEcp1	F, FIB	5
EH9102	Aug-21	Kok River	C	CTX-M-27	Int1	FIA, FIB	15
EK3101	Dec-20	Kham River	B1	CTX-M-55, TEM-116	Int1, ISEcp1	Y	10
EK1201	Jan-21	Kham River	B1	CTX-M-55	Int1, ISEcp1	Y	3
EK1301	Feb-21	Kham River	B1	CTX-M-15	ISEcp1	FIA	34
EK1302	Feb-21	Kham River	F	CTX-M-55, TEM-1	Int1, ISEcp1, Tn3	F, FIB, I1-Iγ	14
EK2302	Feb-21	Kham River	B1	CTX-M-27	-	F, FIB, I1-Iγ	57
EK2303	Feb-21	Kham River	B1	CTX-M-14, TEM-1	Int1, ISEcp1, Tn3	F, FIA, FIB, Y, K	27
EK3304	Feb-21	Kham River	E	CTX-M-55	-	F, FIB	36
EK3305	Feb-21	Kham River	B1	CTX-M-55	ISEcp1	F, FIB	37
EK1401	Mar-21	Kham River	B1	CTX-M-55	Int1	F, FIB, HI2	19
K1506	Apr-21	Kham River	C	CTX-M-14	Int1	Y	47
EK2501	Apr-21	Kham River	D	CTX-M-15, TEM-1	Int1, ISEcp1, Tn3	Y	15
EK2503	Apr-21	Kham River	E	CTX-M-27	Int1	F, FIA, FIB	15
EK2504	Apr-21	Kham River	D	CTX-M-15, TEM-1	Int1, ISEcp1, Tn3	Y	15
EK8301	Jul-21	Kham River	B1	CTX-M-15	ISEcp1	FIIAs	45
EK9101	Aug-21	Kham River	B1	CTX-M-55	Int1	F, FIB, HI2, Y	17

Notes:

^aPhylogroup characterized by clement typing.

^bBeta-lactamase.

^cIntegrons/transposon.

^dPlasmid replicon were determined using PCR.

^eAntibiotic resistance patterns are shown in Table S2.