Table 2. Molecular characteristics of 10 ESBL-producing E. coli.
| Isolate | MLSTa | Serotypesb | Resistance genesc | Plasmidsd | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aminoglycoside | Beta-lactam | Quinolone resistance gene/point mutation | Macrolide, Lincosamind, Streptogramin B | Phenicol | Polymyxin | Sulfonamide | Tetracycline | Trimethoprim | ||||
| EH1201 | 224 | O8:H23 | aac(3)-IId, ant(3″)-Ia | bla CTX-M-14 | gyrA(S83L, D87N), parC(S80I), parE(S458A) | mdf(A), erm(42), erm(B), mph(A) | floR | sul2 | tet(X) | IncFIC(FII), IncX1, IncFIB(AP001918), Col(MG828) | ||
| EH1307 | 13160 | -:H4 | aac(3)-IId, aph(3″)-Ib, aph(6)-Id | bla CTX-M-14 | qnrS1, gyrA(S83L) | mdf(A) | floR | sul2 | tet(A) | p0111, IncFIC(FII), IncA/C2, IncB/O/K/Z, IncFIB(AP001918), ColpVC, Col(MG828) | ||
| EH2102 | 131 | O25:H4 | aadA5 | blaCTX-M-15, blaOXA-1 | aac(6′)-Ib-cr, gyrA(S83L, D87N), parC(S80I, E84V), parE(I529L) | mdf(A), mph(A) | sul1 | tet(A) | dfrA17 | IncFII, IncFIA, Col156, Col(BS512), Col(MG828) | ||
| EH2301 | 1421 | O9:H4 |
aac(3)-IId, aadA2, ant(3″)-Ia, aph(3″)-Ib |
blaCTX-M-55, blaTEM-1B | qnrS1, gyrA(S83L), parC(S80I) | mdf(A), lnu(F) | cmlA1, floR | mcr-1.1 | sul2, sul3 | tet(A), tet(X) | dfrA12 | IncR IncX1, IncX4, |
| EH9101 | 648 | O102:H6 | aac(3)-IIa, aph(6)-Id | blaCTX-M-15, blaOXA-1, blaTEM-1B |
aac(6′)-Ib-cr, gyrA(S83L, D87N), parC(S80I), parE(S458A) |
mdf(A) | sul2 | tet(A) | dfrA14 | IncFII(pRSB107), IncFIB(AP001918), Col(BS512), Col(MG828) | ||
| EK1201 | 224 | O8:H23 |
aac(3)-IIa, aadA2, ant(3″)-Ia, aph(3″)-Ib, aph(6)-Id |
bla CTX-M-55 | gyrA(S83L, D87N), parC(S80I), parE(S458A) | mdf(A) | cmlA1, floR | tet(A), tet(M) | dfrA12 | IncFIB(pHCM2), IncFIA(HI1), IncFIB(K), IncX1, Col440I | ||
| EK2303 | 603 | O175:H16 |
aac(3)-IId, aadA2, aph(3′)-Ia, aph(3″)-Ib, aph(6)-Id |
blaCTX-M-14, blaTEM-1B | gyrA(S83L, D87N), parC(E84K) | mdf(A), lnu(F) | sul2 | tet(B) | IncFIA, IncFIB(AP001918), IncY, Col156, Col(MG828) | |||
| EK2501 | 69 | O17 or O44 or O77:H18 | aph(3″)-Ib, aph(6)-Id | blaCTX-M-15, blaTEM-1B | qnrS1 | mdf(A) | sul2 | tet(A) | dfrA14 | IncY | ||
| EK2504 | 69 | O17 or O44 or O77:H18 | aph(3″)-Ib, aph(6)-Id | blaCTX-M-15, blaTEM-1B | qnrS1 | mdf(A) | sul2 | tet(A) | dfrA14 | IncY | ||
| EK9101 | 5218 | O3:H7 |
aac(3)-IId, aadA2, ant(3″)-Ia, aph(3″)-Ib, aph(6)-Id |
bla CTX-M-55 | qnrS1 | mdf(A) | catA2, cmlA1 | mcr-3.4 | sul2, sul3 | P0111, IncFIB(AP001918), IncI1, IncHI2A, IncHI2 | ||
Notes:
a
MLST determined by https://enterobase.warwick.ac.uk/.
b
Serotype determined by https://cge.food.dtu.dk/services/SerotypeFinder/.
c
The antibiotic resistance genes were search with ResFinder 4.1.
d
The plasmid markers were identified by PlasmidFinder 2.1.