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. 2022 Oct 31;12:984770. doi: 10.3389/fonc.2022.984770

Table 2.

Comparison of clinical characteristics and CT findings between the groups with different absolute difference between the mean contrast-enhanced and nonenhanced attenuation values of thymic cysts.

Parameter Group of Artifactual Hyper-density Group of Unchanged density Group of Artifactual Hypo-density P Value
Total No. of patients (n) 27 38 19
Age (years) 55.9 ± 9.1 51.0 ± 10.6 59.0 ± 12.5 0.023
Sex 0.025
 Men 5 18 10
 Women 22 20 9
Diagnosis-treatment interval time 5.2 ± 2.5 5.3 ± 3.7 4.9 ± 3.0 0.833
Cyst Size
 Total No. of cysts (n) 27 38 19
 Long diameter (mm) 23.7 ± 12.6 36.4 ± 24.7 34.3 ± 29.7 0.086
 Short diameter (mm) 15.5 ± 8.2 24.3 ± 15.4 19.2 ± 11.9 0.025
Nonenhanced CT attenuation
 Total No. of plain scans (n) 27 38 19
 CT attenuation of cysts (HU) 30.7 ± 16.9 32.1 ± 17.6 38.2 ± 17.9 0.322
 CT attenuation of adjacent large vessel (HU) 42.8 ± 7.0 48.7 ± 5.1 48.5 ± 3.9 <0.001
Contrast-enhanced CT attenuation of both arterial and venous phase
 Total No. of arterial and venous phase scans (n) 47 68 25
 CT attenuation of cysts (HU) 46.2 ± 21.7 30.9 ± 18.0 26.6 ± 20.4 <0.001
 CT attenuation of adjacent large vessel (HU) 280.3 ± 68.8 222.5 ± 78.88 249.6 ± 74.2 <0.001

According to the absolute difference in attenuation of the cysts between contrast-enhanced and nonenhanced CT, the patients were classified into the three groups of artifactual hyper-density (> 5 HU), unchanged density (-5~5 HU), and artifactual hypo-density (<-5 HU).