Table 3.
Outcome per tissue | Treatment | Pooled SEM | P-value | ||
---|---|---|---|---|---|
Control | DSS | TBCD + DSS | |||
Ileum | |||||
Villi height, µm | 531.38 | 434.86 | 492.64 | 42.089 | 0.271 |
Crypt depth, µm | 236.72 | 225.98 | 272.66 | 20.130 | 0.203 |
V:C ratio | 2.28 | 2.20 | 1.88 | 0.218 | 0.193 |
Proximal colon | |||||
Mucosal width, µm | 342.23a | 388.93a,b | 586.57b | 70.277 | 0.042 |
Distal colon | |||||
Mucosal width, µm | 377.79a | 646.82b | 714.44b | 42.499 | < 0.001 |
1Pigs were artificially reared from postnatal days 2–28, dosed on postnatal days 14–18, and euthanized on postnatal days 27 or 28 to permit sample collection.
a,bMeans lacking a common superscript letter within a row differ (P < 0.05).
Abbreviations: DSS, dextran sodium sulfate; TBCD, gamma-cyclodextrin-encapsulated tributyrin; V:C, villus height-to-crypt depth.