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. 2022 Sep 26;100(11):skac314. doi: 10.1093/jas/skac314

Table 3.

Effects of orally supplemented TBCD- and DSS-induced colitis on intestinal histomorphology of young pigs1

Outcome per tissue Treatment Pooled SEM P-value
Control DSS TBCD + DSS
Ileum
 Villi height, µm 531.38 434.86 492.64 42.089 0.271
 Crypt depth, µm 236.72 225.98 272.66 20.130 0.203
 V:C ratio 2.28 2.20 1.88 0.218 0.193
Proximal colon
 Mucosal width, µm 342.23a 388.93a,b 586.57b 70.277 0.042
Distal colon
 Mucosal width, µm 377.79a 646.82b 714.44b 42.499 < 0.001

1Pigs were artificially reared from postnatal days 2–28, dosed on postnatal days 14–18, and euthanized on postnatal days 27 or 28 to permit sample collection.

a,bMeans lacking a common superscript letter within a row differ (P < 0.05).

Abbreviations: DSS, dextran sodium sulfate; TBCD, gamma-cyclodextrin-encapsulated tributyrin; V:C, villus height-to-crypt depth.