2. Sensitivity by week after onset of symptoms (IgG, IgM, total Ab).
|
Test groups (true positives/COVID cases) Sensitivity (95% CI) |
|||||
| Target |
Days 1‐7 (week 1) |
Days 8‐14 (week 2) |
Days 15‐21 (week 3) |
Days 22‐28 (week 4) |
Days 29‐35 (week 5) |
| IgGa | 189 (2177/6679) | 202 (5883/9078) | 190 (4328/5027) | 42 (828/940) | 21 (482/531) |
|
27.2 (24.9, 29.7) |
64.8 (62.1, 67.4) |
88.1 (86.6, 89.5) |
92.6 (90.5, 94.3) |
93.5 (90.8, 95.4) |
|
| IgMa | 126 (1770/4492) | 122 (3715/5577) | 118 (2416/3231) | 23 (220/411) | 9 (128/220) |
|
29.5 (25.8, 33.6) |
64.6 (60.3, 68.7) |
78.3 (74.8, 81.4) |
63.8 (56.5, 70.6) |
59.8 (50.5, 68.5) |
|
| IgG/IgMa | 103 (1593/3881) | 96 (2904/3948) | 103 (2571/2929) | 28 (649/734) | 14 (208/225) |
|
41.1 (38.1, 44.2) |
74.9 (72.4, 77.3) |
88.0 (86.3, 89.5) |
91.3 (88.8, 93.3) |
94.4 (90.7, 96.7) |
|
| Total antibodies (Ab)a | 27 (428/1010) | 29 (804/1030) | 33 (908/1016) | 7 (208/233) | 6 (139/147) |
|
37.7 (31.0, 44.9) |
79.4 (74.0, 83.9) |
90.9 (87.8, 93.2) |
94.1 (89.9 96.6) |
97.3 (93.8, 98.8) |
|
| aP values for comparisons across weeks < 0.0001 | |||||
CI: confidence interval