|
Test groups (true positives/COVID cases) Sensitivity (95% CI) |
||||||
| Target |
Days 1‐7 (week 1) |
Days 8‐14 (week 2) |
Days 15‐21 (week 3) |
Days 22‐28 (week 4) |
Days 29‐35 (week 5) |
Convalescent |
| IgAa | 24 (525/1079) | 22 (874/1181) | 19 (424/501) | 5 (52/63) | 1 (4/4) | 22 (959/1257) |
| 44.3 (36.2, 52.8) |
72.9 (65.6, 79.2) |
86.6 (81.2, 90.6) |
89.1 (79.2, 94.6) |
100a (39.8, 100)* |
82.3 (70.0, 90.3) |
|
| IgA/IgGa | 6 (87/167) | 5 (141/170) | 5 (118/125) | 2 (73/74) | 1 (4/4) | 4 (149/157) |
| 48.8 (36.0, 61.8) |
80.8 (70.1, 88.4) |
95.6 (89.9, 98.1) |
99.2 (94.1, 99.9) |
100a (39.8, 100)** |
94.9 (90.1, 97.4) |
|
| IgA/IgM | 1 (49/52) | 1 (36/36) | 1 (43/44) | |||
| 94.2 (83.6, 98.1) |
100a (90.3, 100)** |
97.7a (88.0, 99.9) | ||||
|
aP value for comparison across week to week 5 obtained using ‘melogit’; both P < 0.0001 bEstimates and confidence intervals by summing the counts of true positive and false negative across 2 x 2 tables *95% exact binomial confidence interval **97.5% one‐sided exact binomial confidence interval CI: confidence interval | ||||||
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