Skip to main content
. 2022 Nov 17;2022(11):CD013652. doi: 10.1002/14651858.CD013652.pub2
Test name Test name Suspected of COVID‐19 Current RT‐PCR‐negative Current untested Other/mixed unclear Cross‐reactivity/confounder panels
Test brand Test brand Test groups (true negatives/non‐COVID cases)
Specificity (95% CI)
Lateral flow/colloidal gold
AAZ‐LMB Covid‐Presto test rapid Covid‐19 IgG         1 (63/64)
LFA           98.4a
(91.6, 100)*
ACON Laboratories SARS‐COV‐2 IgG Rapid Test         1 (29/31)
LFA           93.5a
(78.6, 99.2)*
Alfa Scientific CLARITY COVID‐19 IgG Antibody Test         1 (60/60)
LFA           100a
(94.0, 100)**
Augurix Augurix SARS‐CoV‐2 IgG RDT     1 (44/45)    
LFA       97.8a
(88.2, 99.9)*		    
Augurix SimtomaX Corona Check IgG   1 (106/107)      
LFA     99.1a
(94.9, 100)*		      
Avioq Bio‐Tech Novel Coronavirus (2019‐nCov) Antibody IgG Assay Kit       1 (69/72)  
CGIA         95.8a
(88.3, 99.1)*		  
AYTU Biosciences AYTU COVID‐19 IgG Rapid Test Cassette         1 (59/60)
LFA           98.3a
(91.1, 100)*
Beijing Diagreat 2019‐nCoV IgG Antibody Determination Kit 1 (157/160)   1 (573/600)    
FIA   98.1a
(94.6, 99.6)*		   95.5a
(93.5, 97.0)*		    
BioMedomics COVID‐19 IgG Rapid Test         1 (47/51)
LFA           92.1a
(81.1, 97.8)*
BioMerieux Vidas SARS‐CoV‐2 IgG         1 (259/261)
FIA           99.2a
(97.3, 99.9)*
Bioperfectus PerfectPOC Novel Corona Virus (SARS CoV‐2) IgG Rapid Test Kit         1 (39/45)
LFA           86.7a
(73.2, 94.9)*
Biosynex COVID‐19 BSS IgG         1 (27/27)
LFA           100a
(87.2, 100)**
BTNX Rapid ResponseTM COVID‐19 Test Cassette (BTNX Inc.) Kit1 IgG         1 (31/31)
LFA           100a
(88.8, 100)**
Cellex Cellex qSARS‐CoV‐ 2 IgG Cassette Rapid Test         1 (79/79)
LFA           100a
(95.4, 100)**
Clungene Biotech Clungene SARS‐CoV‐2 IgG Rapid Test Cassettes       1 (101/103)  
LFA         98.1a
(93.2, 99.8)*		  
CTK Biotech OnSite COVID‐19 IgG Rapid Test   1 (100/102)   1 (91/92)  
CGIA     98.0a
(93.1, 99.8)*		   98.9a
(94.1, 100)*		  
DecombioBiotechnology Novel Coronavirus (SARS‐CoV‐2) IgG Combo Rapid Test‐Cassette         1 (49/51)
LFA           96.1a
(86.5, 99.5)*
DeepBlue Medical COVID‐19 (SARS CoV‐2) IgG Antibody Test Kit (Colloidal Gold)         1 (44/51)
CGIA           86.3a
(73.7, 94.3)*
DiaCarta QuantiVirus anti‐SARS‐CoV‐2 IgG test         1 (88/88)
FIA           100a
(95.9, 100)**
DNA Link AccuFind COVID19 IgG         1 (59/59)
LFA           100a
(93.9, 100)**
Dynamiker Biotechnology Dynamiker Biotechnology ‐ 2019‐nCOV IgG Rapid Test       1 (102/103)  
LFA         99.0a
(94.7, 100)*		  
Hangzhou Hangzhou unlabelled packaging IgG       1 (90/92)  
CGIA         97.8a
(92.4, 99.7)*		  
Hangzhou Alltest 2019‐nCoV IgG Rapid Test Cassette       2 (192/192) 1 (60/60)
LFA         100a
(98.1, 100)**		 100a
(94.0, 100)**
Hangzhou Biotest RightSign IgG (Also distributed as CoronaChek IgG and Premier Biotech Covid‐19 IgG)   1 (60/65)     2 (110/111)
LFA     92.3a
(83.0, 97.5)*		     99.1
(93.9, 99.9)
Hightop Biotech Hightop SARS‐CoV‐2 IgG Antibody Rapid Test       1 (92/92)  
CGIA         100a
(96.1, 100)**		  
Innovita Biological 2019‐nCoV Ab test IgG         1 (26/28)
LFA           92.9a
(76.5, 99.1)*
InTec Rapid SARS‐CoV‐2 Antibody (IgG) Test         1 (76/79)
CGIA           96.2a
(89.3, 99.2)*
Intelligent Endoscopy Smart screen IgG         1 (60/60)
LFA           100a
(94.0, 100)**
Inzec BIOZEK COVID‐19 IgG/IgM   1 (51/55)      
LFA     92.7a
(82.4, 98.0)*		      
LabOn Time LaboOn Time rapid test cassette IgG       1 (72/72)  
LFA         100a
(95.0, 100)**		  
Liming Bio StrongStep1 SARS‐CoV‐2 IgG       1 (102/103)  
LFA         99.0a
(94.7, 100)*		  
MEDsan GmbH MEDsan COVID‐19 IgG Rapid Test   1 (101/110) 1 (49/50)    
LFA     91.8a
(85.0, 96.2)		 98.0a
(89.4, 99.9)*		    
Multi‐G Multi‐G MGA 2019‐nCoV IgG Rapid test cassette       1 (100/103)  
LFA         97.1a
(91.7, 99.4)*		  
Multi‐G 2019‐nCoV IgG Rapid Test Cassette dual lane   1 (38/39)      
LFA     97.4a
(86.5, 99.9)*		      
Multi‐G 2019‐nCoV IgG Rapid Test Cassette single lane   1 (39/39)      
LFA     100a
(91.0, 100)**		      
NG Biotech NG‐Test IgG COVID‐19 1 (53/55)       1 (28/28)
CGIA   96.4a
(87.5, 99.6)*		       100a
(87.7, 100)*
Nirmidas Biotech Nirmidas COVID‐19 (SARS‐CoV‐2) IgG Antibody Detection Kit         1 (60/60)
LFA           100a
(94.0, 100)**
NTBIO® Diagnostics NTBIO One Step Rapid Test ‐ COVID‐19 IgG Antibody Test   1 (98/108)      
      90.7a
(83.6, 95.5)*		      
Prima Lab Prima COVID‐19 IgG Rapid test       1 (93/103)  
LFA         90.3a
(82.9, 95.2)*		  
Prometheus Bio Prometheus Bio ‐ 2019‐nCoV IgG 1 (24/40)        
LFA   60.0a
(43.3, 75.1)*		        
Qingdao HIGHTOP SARS‐CoV‐2 IgG Ab Rapid Test   1 (111/111)      
      100a
(96.7, 100)**		      
Safecare Biotech SafeCare Bio‐Tech COVID‐19 IgG Rapid Test Device         1 (54/60)
LFA           90.0a
(79.5, 96.2)*
SD Biosensor COVID‐19 IgG Duo     1 (240/242)    
LFA       99.2a
(97.0, 99.9)*		    
Sensing Self Covid‐19 Rapid IgG combined Antibody assay         1 (60/60)
LFA           100a
(94.0, 100)**
Servibio/VEDALAB COVID‐19 Sign IgG         1 (27/27)
LFA           100a
(87.2, 100)**
Sure Biotech SARS‐CoV‐2 IgG Antibody Rapid Test   1 (107/110)     1 (51/51)
LFA     97.3a
(92.2, 99.4)*		     100a
(93.0, 100)**
SureScreen Diagnostics COVID‐19 Coronavirus Rapid Test Cassette IgG   1 (38/39)      
LFA     97.4a
(86.5, 99.9)*		      
T&D Diagnostics Sienna 2019‐nCoV IgG Rapid Test 1 (37/44)        
LFA   84.1a
(69.9, 93.4)*		        
TBG Biotechnology TBG SARS‐CoV‐2 IgG Rapid Test Kit         1 (57/59)
LFA           96.6a
(88.3, 99.6*
UCP Biosciences Coronavirus IgG Antibody (COVID‐19)
Test Cassette		         1 (49/51)
LFA           96.1a
(86.5, 99.5)*
Unknown manufacturer Ready Result IgG         1 (60/60)
LFA           100a
(94.0, 100)**
VivaChek Biotech VivaDiag COVID‐19 IgG Rapid Test       2 (193/195) 1 (47/48)
CGIA         99.0
(96.0, 99.7)		 97.9a
(88.9, 99.9)*
W.H.P.M. COVISURE COVID‐19 IgG Rapid Test         1 (57/59)
LFA           96.6a
(88.3, 99.6)*
Xiamen Biotime SARS‐Cov‐2 IgG Rapid Qualitative Test   1 (91/96)      
LFA     94.8a
(88.3, 98.3)*		      
Zeus Scientific ZEUS SARS‐CoV‐2 IgG/IgM rapid test         1
(60/60)
LFA           100a
(94.0, 100)**
Zhejiang Orient‐Gene COVID‐19 IgG rapid test cassette   1 (39/39) 1 (49/50) 1 (96/103) 1 (78/79)
LFA     100a
(91.0, 100)**		 98.0a
(89.4, 99.9)*		 93.2a
(86.5, 97.2)*		 98.7a
(93.1, 100)*
ELISA
Ash Laboratories Ash Laboratories SARS‐CoV2 IgG ELISA Immunoassay   1 (36/38)     1 (19/19)
      94.7a
(82.3, 99.4)*		     100a
(82.4, 100)**
Beijing Wantai Wantai ELISA IgG assay     1 (100/100)   1 (145/146)
        100a
(96.4, 100)**		   99.3a
(96.2, 100)*
Bio‐Rad Laboratories Novel coronavirus COVID‐19 IgG assay         1 (59/62)
            95.2a
(86.5, 99.0)*
Epitope Diagnostics EDI Novel Coronavirus COVID‐19 IgM ELISA kit 1 (107/110) 1 (104/105)   1 (21/25) 5 (169/178)
    97.3a
(92.2, 99.4)*		 99.0a
(94.8, 100)*		   84.0a
(63.9, 95.5)*		 97.1
(87.8, 99.4)
Euroimmun anti‐SARS‐COV‐2 IgG 5 (478/499) 1 (101/105) 5 (321/325) 8 (523/537) 16 (915/.938)
    95.8
(93.6, 97.2)		 96.2
(90.5, 99.0)		 98.8
(96.8, 99.5)		 97.4
(95.6, 98.5)		 97.7
(96.1, 98.7)
Euroimmun anti‐SARS‐COV‐2 IgG (N‐based)         1 (107/113)
            94.7a
(88.8, 98.0)*
Hotgen Beijing Hotgen SARS‐CoV‐2 IgG ELISA     1 (100/100)    
        100a
(96.4, 100)**		    
Mikrogen Mikrogen IgG anti‐N         1 (109/113)
            96.5a
(91.2, 99.0)*
Vircell COVID‐19 ELISA IgG         1 (19/19)
            100a
(82.4, 100)**
Virotech Virotech SARS‐CoV‐2 ELISA IgG         1 (31/31)
            100a
(88.8, 100)**
Zhuhai Livzon Zhuhai Livzon SARS‐CoV‐2 IgG ELISA   1 (57/60) 2 (218/220)    
      95.0a
(86.1, 99.0)*		 99.1
(96.4, 99.8)		    
CLIA
Abbott Diagnostics Abbott Alinity anti‐SARS‐CoV‐2 nucleocapsid IgG         2(134/135)
            99.3
(94.9, 99.9)
Abbott Diagnostics Abbott Architect anti‐SARS‐CoV‐2 nucleocapsid IgG 5 (382/394) 5 (673/675) 1 (239/243) 1 (73/73) 13 (1060/1070)
    98.2
(92.0, 99.6)		 99.7
(98.8, 99.9)		 98.4a
(95.8, 99.5)*		 100a
(95.1, 100)**		 99.1
(97.9, 99.6)
Autobio Diagnostics SARS‐CoV‐2 CLIA Microparticles IgM/IgG   1 (3777/3789)      
      99.7a
(99.4, 99.8)*		      
Beckman Coulter Beckman Coulter ‐ Access SARS‐CoV‐2 IgG   1 (62/62)     1 (97/100)
      100a
(94.2, 100)**		     97.0a
(91.5, 99.4)*
DiaSorin Diasorin LIAISON SARS‐CoV‐2 S1/S1 IgG CLIA 1 (179/183) 2 (184/186)   1 (29/30) 10 (642/671)
    97.8a
(94.5, 99.4)*		 98.9
(95.8, 99.7)		   96.7a
(82.8, 99.9)*		 97.9
(94.2, 99.3)
Diazyme Diazyme DZ‐LITE 2019‐nCoV IgG (CLIA) Assay Kit         1 (49/49)
            100a
(92.7, 100)**
Hunan Yuanjing COVID‐19 IgG Detection Kits 1 (39/40)        
    97.5a
(86.8, 99.9)*		        
MEXACARE GmbH QuickTestCorona COVID‐19 IgG   1 (108/109)      
      99.1a
(95.0, 100)*		      
Ortho Clinical Diagnostics Vitros (VITROS) Anti‐SARS‐Cov‐2 Total assay IgG   1 (105/105)     2 (174/175)
      100a
(96.5, 100)**		     99.4
(96.1, 99.9)
Shenzhen YHLO YHLO iFlash IgG assay 1 (30/33) 2 (1053/1082) 1 (581/586)   1 (74/75)
    90.9a
(75.7, 98.1)*		 97.3a
(96.2, 98.1)*		 99.1a
(98.0, 99.7)*		   98.7a
(92.8, 100)*
SNIBE Shenzhen MAGLUMI 2019‐nCoV IgG kits 1 (10/11)     1 (72/72) 4 (207/211)
    90.9a
(58.7, 99.8)*		     100a
(95.0, 100)**		 98.6
(85.2, 99.9)
Vircell COVID‐19 VIRCLIA IgG MONOTEST       1 (31/33)  
          93.9a
(79.8, 99.3)*		  
Unclear/unknown
Vibrant America Vibrant COVID‐19 Ab IgG       1 (5250/5262)  
          99.8a
(99.6, 99.9)*		  
aEstimates and confidence intervals by summing the counts of true‐negative and false‐positive across 2 x 2 tables
*95% exact binomial confidence interval
**97.5% one‐sided exact binomial confidence interval
Ab: antibodyCI: confidence intervals
CGIA: colloidal gold immunoassayCLIA: chemiluminescence immunoassay
DNA: deoxyribonucleic acidELISA: enzyme‐linked immunosorbent assay
FIA: fluorescence immunoassay
LFA: lateral flow assayMIA: magnetic immunoassay
RT‐PCR: reverse transcription polymerase chain reaction