Table 1. Characteristics of patients with ectopic pregnancies treated with methotrexate (N=73).
* Median (IQR). For gestational age, size of ectopic, baseline β-hCG level skewed to the right.
POD: Pouch of Douglas; MTX: Methotrexate; β-hCG: beta-human Chorionic Gonadotropin; BTL: Bilateral Tubal Ligation; IUCD: Intrauterine Contraceptive Device; C-Section: Cesarean section delivery.
| Characteristic | Mean (SD) | n (%) |
| Sociodemographic | ||
| Age (years) | 30.67 (5.15) | |
| Age group (years) | ||
| < 25 | 7 (9.6) | |
| 25 – 29 | 26 (35.6) | |
| 30 – 35 | 25 (34.2) | |
| > 35 | 15 (20.5) | |
| Ethnicity | ||
| Malay | 47 (64.4) | |
| Chinese | 11 (15.1) | |
| Indian | 9 (12.3) | |
| Others | 6 (8.2) | |
| Marital status | ||
| Married | 71 (97.3) | |
| Not married | 2 (2.7) | |
| Occupation | ||
| Employed | 50 (68.5) | |
| Self-employed | 6 (8.2) | |
| Unemployed | 17 (23.3) | |
| Current obstetric history | ||
| Gravida | ||
| 1 | 16 (21.9) | |
| 2 | 25 (34.2) | |
| 3 | 8 (11.0) | |
| 4 | 10 (13.7) | |
| > 5 | 14 (19.2) | |
| Parity | ||
| 0 | 28 (38.4) | |
| 1 | 22 (30.1) | |
| 2 | 11 (15.1) | |
| 3 | 11 (15.1) | |
| 4 | 1 (1.4) | |
| Gestational age (weeks) | 7.00 (2.00) * | |
| Location of ectopic pregnancy | ||
| Tubal | 48 (65.8) | |
| Cornual | 5 (6.8) | |
| Cervical | 3 (4.1) | |
| Cesarean scar | 17 (23.3) | |
| Size of ectopic pregnancy (cm) | 2.11 (0.89) * | |
| Size of ectopic pregnancy | ||
| < 3.5 cm | 64 (87.7) | |
| > 3.5 cm | 9 (12.3) | |
| Yolk sac | ||
| Absent | 40 (54.8) | |
| Present | 33 (45.2) | |
| Fetal cardiac activities | ||
| Absent | 61 (83.6) | |
| Present | 12 (16.4) | |
| Free fluid at POD | ||
| Absent | 56 (76.7) | |
| Present | 17 (23.3) | |
| Route of MTX | ||
| Intramuscular | 52 (71.2) | |
| Transvaginal / Transcervical | 20 (27.4) | |
| Laparoscopic | 1 (1.4) | |
| Baseline b-hCG | 2449.00 (6056.00) * | |
| Baseline b-hCG level | ||
| < 1500 | 10 (13.7) | |
| 1500 – 4999 | 42 (57.5) | |
| 5000 – 9999 | 5 (6.8) | |
| 10,000 – 100,000 | 13 (17.8) | |
| > 100,000 | 3 (4.1) | |
| Past obstetric history | ||
| Previous abortion | ||
| No | 45 (61.6) | |
| Yes | 28 (38.4) | |
| Previous ectopic pregnancy | ||
| No | 63 (86.3) | |
| Yes | 10 (13.7) | |
| Post BTL | ||
| No | 73 (100.0) | |
| Yes | 0 (0.0) | |
| IUCD usage | ||
| No | 72 (88.6) | |
| Yes | 1 (1.4) | |
| History of infertility | ||
| No | 67 (91.8) | |
| Yes | 6 (8.2) | |
| Past gynecology history | ||
| Previous non-tubal abdominal surgery | ||
| No | 71 (97.3) | |
| Yes | 2 (2.7) | |
| Previous pelvic surgery | ||
| No | 71 (97.3) | |
| Yes | 2 (2.7) | |
| Previous tubal surgery | ||
| No | 64 (87.7) | |
| Yes | 9 (12.3) | |
| History of C-Section | ||
| No | 48 (65.8) | |
| Yes | 25 (34.2) | |
| Number of C-section | ||
| 0 | 48 (65.8) | |
| 1 | 15 (20.5) | |
| 2 | 9 (12.3) | |
| 3 | 1 (1.4) |