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. 2022 Nov 3;16:1000179. doi: 10.3389/fnins.2022.1000179

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Copyright © 2022 Peng, Kobeissy, Mondello, Barsa and Mechref.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of common dissociation methods used in CNS diseases. (A) CID of bi-antennary sialylated and fucosylated N-glycan derived from IgG of PD patients. (B) CID of sulfated O-glycan derived from nigrostriatal tissue of PD patients. (C) HCD of tri-antennary tri-sialylated N-glycan derived from neuroblastoma cell line. Reproduced with the modification and permissions of panel (A) from Russell et al. (2017), panel (B) from Wilkinson et al. (2021), and panel (C) from Hu et al. (2015).