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Induction of RTC apoptosis in IL-12-primed mice by challenge with TNF-α and its inhibition by anti-IFN-γ antibody. IL-12-primed mice were injected with TNF-α alone (a), TNF-α and anti-IFN-γ antibody (b), or anti-IFN-γ antibody alone (c). The kidneys were subjected to the specific labeling of fragmented DNA. Magnification, ×200.
