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. Author manuscript; available in PMC: 2022 Nov 17.
Published in final edited form as: J Comput Assist Tomogr. 2020 Jul-Aug;44(4):562–568. doi: 10.1097/RCT.0000000000001022

Table 4.

Sensitivity analysis for Estimating the association between medication use and vertebra BMD (mg/cm3)

β (Se) 95% CI P-value

No NSAID or ASA use Reference
ASA User (all) 0.59(1.69) −2.72, 3.89 0.72
Regular use, low dose ASA 2.54(2.62) −2.61, 7.68 0.33
Occasional use ASA −2.41(3.50) −9.28,4.47 0.49
Regular use, high dose ASA 1.03(2.01) −2.92, 4.97 0.61
Non-selective NSAIDs use −0.57(1.93) −4.35, 3.21 0.77
Cox 2 selective NSAID use 6.58(2.93) 0.83, 12.33 0.02
*

Sensitivity analysis using stronger age adjustments, multiple imputation for missing values in BMD reads, and looking at other medications in the non-steroidal anti-inflammatory drug (NSAID) class.

Abbreviations: BMD, bone mineral density; CI, confidence interval; NSAID, non-steroidal anti-inflammatory drug; ASA, aspirin; Std, Standard

β stands for the absolute value change of thoracic BMD