Table 3.
Univariate and Multivariate Models of ACE2 Messenger RNA Associations in the RISK Cohort
| ACE2 (RPKM)a | Univariate |
Multivariate |
||
|---|---|---|---|---|
| β | P value | β | P value | |
| All (n = 322) | ||||
| Age at diagnosis | 2.745 | .0963 | 3.368 | .023 |
| Disease status (non-IBD) | 109.922 | 9.78e-14 | 113.091 | 2.14e-14 |
| Disease status (UC) | 73.518 | 3.13e-09 | 72.099 | 5.30e-09 |
| Sex (male) | –3.042 | .774 | –3.522 | .70886 |
| CD only (n = 218) | ||||
| Age at diagnosis | 1.464 | .388 | 1.1361 | .494 |
| Sex (male) | –0.196 | .985 | 0.9999 | .922 |
| CD type (iCD) | –41.12 | 4.86e-04 | –40.7184 | 5.93e-04 |
RPKM, reads per kilobase million.
a
Tested variables are indicated in parentheses.