Figure 2.

Monkeypox clinical presentations and differential diagnosis

Discrete rash on the thorax caused by monkeypox (Nigeria; A) and varicella (Spain; B); a generalised monkeypox rash (Democratic Republic of the Congo; C) and a blistering rash caused by dermatitis herpetiformis (Spain; D); localised monkeypox lesions causing penile oedema (Spain; E) and impetigo associated with scabies (Malawi; F); localised perianal rash caused by monkeypox (Spain; G) and molluscum contagiosum (Spain, H); a solitary monkeypox genital ulcer (Spain; I) and a primary syphilis chancre (Spain; J); lip lesion caused by monkeypox (Spain; K) and herpes simplex (Spain; L); hand lesions caused by monkeypox (Spain; M) and Orf virus infection (Spain; N); monkeypox lesions on the tongue (Spain; O) and aphthous ulcer on the labial mucosa (Spain; P). Photo credits: Dimie Ogoina (A), Fernando Gruber (B), Cristina Galván (C, D, F, H, N, P), Adrià Mendoza (E), José Miguel Cabrera (G, K, O), Irene Fuertes (I, M), Martí Vall-Mayans (J), and Rosa Taberner (L).