Table 2.
Concentration levels (mean ± SD (median; interquartile ranges (IQR) 25–75); ng/ml) of apolipoproteins in the AH diabetic patients without and with different stages of DR.
| Non-apparent DR (n = 23) | Mild/moderate NPDR (n = 13) |
Advanced NPDR/PDR (n = 14) |
p1 | p2 | |
|---|---|---|---|---|---|
| Apo AI | 421 ± 446 (235; 93-801) |
855 ± 761 (543; 288-1572) |
2427 ± 1288 (2494; 1328-3393) |
<0.0001∗ | 0.0015∗ |
| Apo AII | 178 ± 191 (104; 40.1-293) |
299 ± 262 (221; 106-477) |
802 ± 427 (870; 320-1092) |
<0.0001∗ | 0.0058 |
| Apo CI | 60 ± 49 (42; 22-108) |
89 ± 55 (80; 46-129) |
195 ± 81 (210; 126-275) |
<0.0001∗ | 0.005 |
| Apo CIII | 4.0 ± 4.5 (2.2; 1.0-5.8) |
6.4 ± 4.9 (4.6; 1.9-11.3) |
27.3 ± 23.5 (26.3; 8.3-40.8) |
0.00027∗ | 0.0098 |
| Apo D | 34 ± 17 (29; 17-50) |
51 ± 32 (39;26-74) |
114 ± 54 (114; 84-132) |
0.00011∗ | 0.0046 |
| Apo E | 95 ± 73 (79; 41-127) |
118 ± 76 (82; 57-188) |
226 ± 113 (226;155-296) |
0.0023∗ | 0.0326 |
| Apo H | 664 ± 539 (484; 275-943) |
1475 ± 885 (1238; 569-2434) |
4223 ± 2836 (3177; 1761-6906) |
<0.0001∗ | 0.0015∗ |
| Apo J | 640 ± 452 (564; 302-805) |
945 ± 885 (465; 366-1468) |
1520 ± 759 (1548; 1010-1925) |
0.00526 | 0.1280 |
Abbreviations: AH: aqueous humor; p1: p value between nonapparent DR and advanced NPDR/PDR. p2: p value between mild/moderate NPDR and advanced NPDR/PDR. ∗p value remained significant after application of the Holm correction.