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Enzymatic metabolic stability of the active derivative 27 compared with Propranolol and Terfenadine.
| Compound ID | Mean CLint (μL/min/mg) | Mean t1/2 (min) | Metabolic rate |
|---|---|---|---|
| Terfenadine | 570.30 | 8.41 | High |
| Propranolol | 46.20 | 143.80 | Low |
| 27 | 54.60 | 133.51 | Intermediate |
