Table 2.
HRs, 95% CI and P values for 75th step count percentile versus 25th percentile with respect to each continuous Cox model and diagnosis
| Model/diagnosis | Sample size (N) | Events (n) | 25th percentile (thousands) | 75th percentile (thousands) | HR (75% versus 25%) | 95% CI | P value |
|---|---|---|---|---|---|---|---|
| Model 1 | |||||||
| Diabetes | 5,124 | 156 | 6.05 | 10.63 | 0.44 | 0.28, 0.68 | <0.001 |
| Hypertension | 4,437 | 482 | 6.18 | 10.73 | 0.71 | 0.55, 0.91 | 0.007 |
| GERD | 4,613 | 432 | 6.14 | 10.76 | 0.64 | 0.56, 0.73 | <0.001 |
| MDD | 4,884 | 467 | 6.09 | 10.72 | 0.63 | 0.55, 0.72 | <0.001 |
| Obesity | 4,774 | 368 | 6.16 | 10.77 | 0.52 | 0.43, 0.62 | <0.001 |
| Sleep apnea | 4,922 | 348 | 6.11 | 10.70 | 0.53 | 0.45, 0.63 | <0.001 |
| Model 2 | |||||||
| Diabetes | 5,124 | 156 | 6.05 | 10.63 | 0.68 | 0.56, 0.84 | <0.001 |
| Hypertension | 4,437 | 482 | 6.18 | 10.73 | 0.76 | 0.59, 0.98 | 0.033 |
| GERD | 4,613 | 432 | 6.14 | 10.76 | 0.66 | 0.57, 0.76 | <0.001 |
| MDD | 4,884 | 467 | 6.09 | 10.72 | 0.66 | 0.57, 0.76 | <0.001 |
| Obesity | 4,774 | 368 | 6.16 | 10.77 | 0.59 | 0.43, 0.82 | 0.001 |
| Sleep apnea | 4,922 | 348 | 6.11 | 10.70 | 0.48 | 0.35, 0.65 | <0.001 |
| Model 3 | |||||||
| Diabetes | 5,124 | 156 | 6.05 | 10.63 | 0.67 | 0.54, 0.83 | <0.001 |
| Hypertension | 4,437 | 482 | 6.18 | 10.73 | 0.75 | 0.58, 0.98 | 0.031 |
| GERD | 4,613 | 432 | 6.14 | 10.76 | 0.64 | 0.55, 0.74 | <0.001 |
| MDD | 4,884 | 467 | 6.09 | 10.72 | 0.67 | 0.59, 0.78 | <0.001 |
| Obesity | 4,774 | 368 | 6.16 | 10.77 | 0.59 | 0.42, 0.81 | 0.001 |
| Sleep apnea | 4,922 | 348 | 6.11 | 10.70 | 0.54 | 0.45, 0.64 | <0.001 |
| Model 4 | |||||||
| Diabetes | 5,124 | 156 | 6.05 | 10.63 | 0.77 | 0.69, 1.0 | <0.05 |
| Hypertension | 4,437 | 482 | 6.18 | 10.73 | 0.81 | 0.61, 1.07 | 0.14 |
| GERD | 4,613 | 432 | 6.14 | 10.76 | 0.71 | 0.59, 0.84 | <0.001 |
| MDD | 4,884 | 467 | 6.09 | 10.72 | 0.69 | 0.58, 0.82 | <0.001 |
| Obesity | 4,774 | 368 | 6.16 | 10.77 | 0.56 | 0.40, 0.80 | 0.001 |
| Sleep apnea | 4,922 | 348 | 6.11 | 10.70 | 0.49 | 0.35, 0.68 | <0.001 |
| Model 5 | |||||||
| Diabetes | 5,124 | 156 | 6.05 | 10.63 | 0.78 | 0.59, 1.02 | 0.07 |
| Hypertension | 4,437 | 482 | 6.18 | 10.73 | 0.82 | 0.62, 1.08 | 0.158 |
| GERD | 4,613 | 432 | 6.14 | 10.76 | 0.71 | 0.59, 0.86 | <0.001 |
| MDD | 4,884 | 467 | 6.09 | 10.72 | 0.70 | 0.59, 0.84 | <0.001 |
| Obesity | 4,774 | 368 | 6.16 | 10.77 | 0.56 | 0.40, 0.79 | 0.001 |
| Sleep apnea | 4,922 | 348 | 6.11 | 10.70 | 0.49 | 0.35, 0.68 | <0.001 |
Model 1 included steps (time-varying), age, race and sex. Model 2 = Model 1 plus systolic blood pressure, CAD, cancer, smoking, education, alcohol and body mass index. Model 3 = Model 2 plus Fitbit wear time (time-varying). Model 4 = Model 2 plus baseline step counts (averaged over first 3 months). Model 5 = Model 2 plus baseline step counts (averaged over first 6 months).