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. 2022 Aug 25;28(11):2374–2380. doi: 10.1038/s41591-022-01977-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, Kaplan–Meier OS curves of all patients. b, Forest plots of OS by subgroups. c, Kaplan–Meier PFS curves of all patients. d, Forest plots of PFS by subgroups. Median OS and PFS and corresponding two-sided 95% CIs were estimated by the Kaplan–Meier method. HRs and corresponding two-sided 95% CIs for OS and PFS were calculated using a stratified Cox proportional hazard model with Efron’s method of tie handling. Cemi, cemiplimab; chemo, chemotherapy; met, metastasis; PBO, placebo.