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. 2022 Nov 10;28(11):2381–2387. doi: 10.1038/s41591-022-02049-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — a, Cognitive trajectories of mPACC5 scores over time in the different AT categories in each individual cohort. b, Cognitive trajectories of MMSE scores over time in the different AT categories in each individual cohort. The average regression line for each group was plotted from linear mixed effect models including age, sex, and education as covariates. The error bands correspond to the 95% confidence interval. Data are anchored to the tau-PET visit (Time 0), and cognitive data up to 1 year prior to PET was included.