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. 2022 Nov 10;28(11):2381–2387. doi: 10.1038/s41591-022-02049-x

Table 1.

Participant characteristics

AT A+T A+TMTL+ A+TNEO-T+ P
n 843 328 55 65
Age, years 68.6 ± 9.6 75.5 ± 8.2 75.6 ± 6.6 76.4 ± 6.8 <0.001a
Sex, n (%) male 424 (50.3) 164 (50.0) 24 (43.6) 31 (47.7) 0.822
Education, years 14.7 ± 3.1 14.6 ± 3.1 13.7 ± 3.8 13.9 ± 3.5 0.02b
Follow-up duration, months 43.0 ± 18.9 40.1 ± 17.6 39.0 ± 16.5 36.4 ± 14.9 0.004c
Follow-up visits, number 4.1 ± 1.5 4.1 ± 1.4 4.0 ± 1.3 3.6 ± 1.2 0.07
MMSE, baseline score 29.0 ± 1.0 28.7 ± 1.3 28.3 ± 1.5 28.2 ± 1.3 <0.001d
Progression to MCI, n (%) 26 (8.9%) 26 (3.3%) 25 (49.0%) 32 (53.3%) <0.001
Progression to all-cause dementia, n (%) 4 (0.5%) 3 (1.0%) 2 (3.9%) 12 (20.0%) <0.001

P values from two-sided statistical tests were reported. ANOVAs were used for continuous variables and chi-squared tests were used for categorical variables. Post-hoc tests were adjusted using Bonferroni correction.

aA+TNEO-T+ and A+TMTL+ and A+T > AT b post-hoc tests revealed no significant group differences, cAT > A+TNEO-T+, dA+TNEO-T+, A+TMTL+ and A+T < AT and A+TNEO-T+ < A+ T-.