Table 1.
Participant characteristics
A−T− | A+T− | A+TMTL+ | A+TNEO-T+ | P | |
---|---|---|---|---|---|
n | 843 | 328 | 55 | 65 | |
Age, years | 68.6 ± 9.6 | 75.5 ± 8.2 | 75.6 ± 6.6 | 76.4 ± 6.8 | <0.001a |
Sex, n (%) male | 424 (50.3) | 164 (50.0) | 24 (43.6) | 31 (47.7) | 0.822 |
Education, years | 14.7 ± 3.1 | 14.6 ± 3.1 | 13.7 ± 3.8 | 13.9 ± 3.5 | 0.02b |
Follow-up duration, months | 43.0 ± 18.9 | 40.1 ± 17.6 | 39.0 ± 16.5 | 36.4 ± 14.9 | 0.004c |
Follow-up visits, number | 4.1 ± 1.5 | 4.1 ± 1.4 | 4.0 ± 1.3 | 3.6 ± 1.2 | 0.07 |
MMSE, baseline score | 29.0 ± 1.0 | 28.7 ± 1.3 | 28.3 ± 1.5 | 28.2 ± 1.3 | <0.001d |
Progression to MCI, n (%) | 26 (8.9%) | 26 (3.3%) | 25 (49.0%) | 32 (53.3%) | <0.001 |
Progression to all-cause dementia, n (%) | 4 (0.5%) | 3 (1.0%) | 2 (3.9%) | 12 (20.0%) | <0.001 |
P values from two-sided statistical tests were reported. ANOVAs were used for continuous variables and chi-squared tests were used for categorical variables. Post-hoc tests were adjusted using Bonferroni correction.
aA+TNEO-T+ and A+TMTL+ and A+T− > A−T− b post-hoc tests revealed no significant group differences, cA−T− > A+TNEO-T+, dA+TNEO-T+, A+TMTL+ and A+T− < A−T− and A+TNEO-T+ < A+ T-.