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. 2022 Sep 22;28(11):2309–2320. doi: 10.1038/s41591-022-01980-3

Extended Data Fig. 8. Global metabolite importances for each metabolite and endpoint.

Extended Data Fig. 8

Heatmap of the metabolite importances, represented by absolute global SHAP value estimates per endpoint for the 168 circulating metabolites. The endpoints are sorted by the discriminative performance of the metabolomic state (left to right, see Fig. 3a). MACE - Major Adverse Cardiac Events, CHD - Coronary Heart Disease, PAD - Peripheral Artery Disease, AAA - Abdominal Aortic Aneurysm, COPD - Chronic Obstructive Pulmonary Disease.