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. 2022 Sep 22;28(11):2309–2320. doi: 10.1038/s41591-022-01980-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — Discriminative performance is stratified by endpoint, age at recruitment, biological sex, and self-reported ethnic background. As the concordance index is only reliable if a sufficient number of events are recorded, subgroups with < 100 events were excluded. The number of events and eligible individuals is indicated at the top of each panel. Data are presented as median (center of error bar) and 95% CI (line of error bar) determined by bootstrapping with 1000 iterations.