Figure 1.
Volcano plot of murine IC RT2 profiler antibacterial PCR array. Murine ICs were enriched by flowsorting from “IC reporter” mice following exposure to UPEC versus saline in vivo for 1‐h. Data are presented as volcano plot to identify significant gene expression changes in UPEC exposed ICs as compared to saline. Thresholds for the volcano plot were a fold change of >2 and p‐value of <0.05. Dotted lines represent significance. Upper right quadrant next to dotted lines has genes which are significant and upregulated. Genes listed on lower right are upregulated but not significant. Genes listed on upper left quadrant are significantly downregulated and genes listed in lower left quadrant are downregulated but not significant. n = 3 “IC reporter” mice/group. IC, intercalated cell; UPEC, uropathogenic Escherichia coli.