KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Antibodies | ||
| Anti-tyrosine hydroxylase (TH) | EMD Millipore | RRID: AB_390204 |
| Alexa Fluor 594 goat anti-rabbit secondary antibody | Invitrogen | RRID: AB_2534079 |
| Bacterial and virus strains | ||
| AAV9-hSyn-GRABDA2m | Vigene Biosciences | YL002009-AV9-PUB |
| AAV5-CAG-tdTomato | UNC Vector Core | AAV In Stock Vectors: Ed Boyden |
| AAV5-CAG-GFP | UNC Vector Core | AAV In Stock Vectors: Ed Boyden |
| Chemicals, peptides, and recombinant proteins | ||
| 6-Hydroxydopamine hydrochloride | Sigma-Aldrich | H4381 |
| Deposited data | ||
| Matlab codes | This paper | GitHub (https://github.com/ckakiti/Novelty_paper_2021) |
| Video tracking and dopamine fluorometry data | This paper | Dryad (doi:10.5061/dryad.41ns1rnh2) |
| Experimental models: Organisms/strains | ||
| Mouse: C57BL/6J | Jackson Laboratory | RRID: IMSR_JAX:000664 |
| Software and algorithms | ||
| DeepLabCut | Mathis et al., 2018 | https://github.com/DeepLabCut/DeepLabCut |
| MoSeq | Wiltschko et al., 2015 | https://dattalab.github.io/moseq2-website/index.html |
| MATLAB | MathWorks | RRID:SCR_001622 |
| LabView | National Instruments | RRID:SCR_014325 |
| Other | ||
| Novelty object: LEGO | Mega Bloks | DCH63 |
| Novelty object: rubber toy | Kong Classic, M | https://www.kongcompany.com/kong-classic |
| Lighting in Novelty arena | Home Depot | https://www.homedepot.com/p/Westek-Indoor-Outdoor-6-ft-White-LED-Rope-Light-Kit-LROPE6W/312080910?source=shoppingads&locale=en-US#overlay |
| Camera in Novelty arena | Xbox | [discontinued] https://www.target.com/p/xbox-one-stand-alone-kinect-sensor/-/A-16504446?AFID=google_pla_df&CPNG=PLA_Electronics%20Shopping&LID=700000001170770pgs&adgroup=SC_Electronics&device=c&gclid=EAIaIQobChMIybe75biQ3QIVCFYNCh2wtADUEAQYAiABEgJ0XvD_BwE&gclsrc=aw.ds&location=9001999&network=g&ref=tgt_adv_XS000000 |
| Camera adaptor | Xbox | https://www.amazon.com/perseids-Adapter-Windows-Interactive-Development/dp/B07CWQK6XG/ref=sr_1_5?ie=UTF8&keywords=inect%20adapter%20pc&qid=1535484053&sr=8-5 |
| Novelty arena: Frame | McMaster-Carr | https://www.mcmaster.com/47065T101 |
| Novelty arena: Walls/floor (outside) | McMaster-Carr | https://www.mcmaster.com/8505k744 |
| Novelty arena: Walls (inside) | McMaster-Carr | https://www.thorlabs.com/thorproduct.cfm?partnumber=BFP1 |
| Novelty arena: Floor (inside) | McMaster-Carr | https://www.walmart.com/ip/Five-Star-2-Pocket-Stay-Put-Plastic-Folder-Red-72109/310380845 |
| Repository with instructions for running code | This paper | https://github.com/ckakiti/Novelty_paper_2021 |