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. 2022 Nov 17;12:19740. doi: 10.1038/s41598-022-22465-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Differential expressed genes FC > 2 FDR < 0.05. (B) Venn diagram of DEGs with |FC|> 2 and FDR < 0.05. UC lesional tissue vs. nonlesional tissue/PS lesional tissue vs. nonlesional tissue. (B) Top 50 upregulated PS DEGs among unique PS genes. (C) Top 50 upregulated UC DEGs among unique UC genes. (D) Top 50 upregulated PS DEGs among shared UC and PS genes. (E) Top 50 upregulated UC DEGs among shared UC and PS genes. There are 35 differentially expressed genes for both diseases but in different directions, what makes up/down numbers differ from the total number of DEGs.