Table 4.
Genes in the shared signature significantly correlated (p < 0.05) with UC disease activities (Mayo scores).
| Symbol | UC inflamed vs. non-inflamed | Inflamed | Non-inflamed | ||||
|---|---|---|---|---|---|---|---|
| log2FC | pvalue | fdr | pvalue | Correlation coefficient | pvalue | Correlation coefficient | |
| FADS1 | 1.72 | 1.97E−16 | 8.78E−28 | 0.00E+00 | 0.61 | 3.70E−01 | 0.23 |
| FADS2 | 2.13 | 2.92E−10 | 3.14E−22 | 1.00E−02 | 0.56 | 1.60E−01 | 0.35 |
| CHI3L2 | 2.63 | 1.91E−22 | 4.86E−21 | 1.00E−02 | 0.54 | 3.30E−01 | − 0.24 |
| FIBIN | 1.82 | 3.04E−18 | 3.96E−17 | 1.00E−02 | 0.54 | 3.10E−01 | 0.25 |
| CH25H | 1.32 | 5.22E−18 | 6.52E−17 | 1.00E−02 | 0.53 | 7.20E−01 | 0.09 |
| HSD11B1 | 1.95 | 3.41E−13 | 1.62E−15 | 3.00E−02 | 0.48 | 5.00E−02 | 0.47 |
| CXCL6 | 3.82 | 1.17E−24 | 4.58E−23 | 4.00E−02 | 0.45 | 3.00E−02 | 0.5 |
| SLC7A5 | 1.61 | 4.44E−22 | 1.06E−20 | 4.00E−02 | 0.45 | 2.70E−01 | 0.27 |
| TESC | 1.83 | 1.35E−32 | 3.89E−30 | 4.00E−02 | 0.45 | 4.80E−01 | − 0.18 |