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. 2022 Nov 4;9:1026597. doi: 10.3389/fcvm.2022.1026597

TABLE 6.

The cumulative incidence rates of major adverse cardiovascular and cerebral events per the annual height decrease rate in female patients based on menopausal status.

No Yes

Annual rate of height decrease†† Annual rate of height decrease††

Group 1 Group 2 Group 3 Group 1 Group 2 Group 3


(N = 9,070) (N = 1,939) (N = 1,098) (N = 45,431) (N = 8,605) (N = 3,807)


Cumulative incidence rate n (%) n (%) n (%) n (%) n (%) n (%)
MACCE
1st year 14 (0.2) 0 (0.0) 0 (0.0) 377 (0.8) 108 (1.3) 53 (1.4)
2nd year 31 (0.3) 1 (0.1) 2 (0.2) 780 (1.7) 214 (2.5) 103 (2.7)
3rd year 50 (0.6) 4 (0.2) 6 (0.6) 1,173 (2.6) 321 (3.7) 165 (4.3)
4th year 68 (0.8) 7 (0.4) 7 (0.6) 1,577 (3.5) 440 (5.1) 225 (5.9)
All 163 (1.8) 12 (0.6) 15 (1.4) 3,907 (8.6) 1,083 (12.6) 546 (14.3)
Cardiac death
1st year 0 (0.0) 0 (0.0) 0 (0.0) 6 (0.0) 2 (0.0) 3 (0.1)
2nd year 2 (0.0) 0 (0.0) 0 (0.0) 25 (0.1) 5 (0.1) 3 (0.1)
3rd year 6 (0.1) 0 (0.0) 1 (0.1) 49 (0.1) 13 (0.2) 11 (0.3)
4th year 7 (0.1) 0 (0.0) 1 (0.1) 83 (0.2) 23 (0.3) 22 (0.6)
All 15 (0.2) 0 (0.0) 2 (0.2) 163 (0.4) 43 (0.5) 39 (1.0)
Non-fatal MI
1st year 1 (0.0) 0 (0.0) 0 (0.0) 29 (0.1) 11 (0.1) 4 (0.1)
2nd year 3 (0.0) 0 (0.0) 0 (0.0) 70 (0.2) 22 (0.3) 9 (0.2)
3rd year 4 (0.0) 0 (0.0) 0 (0.0) 109 (0.2) 31 (0.4) 14 (0.4)
4th year 6 (0.1) 0 (0.0) 0 (0.0) 147 (0.3) 45 (0.5) 20 (0.5)
All 14 (0.2) 0 (0.0) 0 (0.0) 355 (0.8) 109 (1.3) 47 (1.3)
Stroke
1st year 13 (0.1) 0 (0.0) 0 (0.0) 330 (0.7) 92 (1.1) 42 (1.1)
2nd year 26 (0.3) 1 (0.1) 1 (0.1) 665 (1.5) 182 (2.1) 88 (2.3)
3rd year 41 (0.5) 3 (0.2) 3 (0.3) 991 (2.2) 268 (3.1) 135 (3.6)
4th year 56 (0.6) 6 (0.3) 4 (0.4) 1,300 (2.9) 359 (4.2) 176 (4.6)
All 136 (1.5) 10 (0.5) 8 (0.7) 3,286 (7.2) 901 (10.5) 441 (11.6)
Hospitalization for HF
1st year 0 (0.0) 0 (0.0) 0 (0.0) 21 (0.1) 5 (0.1) 5 (0.1)
2nd year 0 (0.0) 0 (0.0) 1 (0.1) 47 (0.1) 10 (0.1) 7 (0.2)
3rd year 1 (0.0) 1 (0.1) 3 (0.3) 73 (0.2) 22 (0.3) 15 (0.4)
4th year 1 (0.0) 1 (0.1) 3 (0.3) 117 (0.3) 36 (0.4) 22 (0.6)
All 2 (0.0) 2 (0.1) 7 (0.6) 258 (0.6) 73 (0.9) 49 (1.3)

MACCE, major adverse cardiovascular and cerebral events; MI, myocardial infarction; HF, heart failure.

After observing the degrees of height reduction for 10 years from 2002, we annually calculated cumulative incidence rate of MACCE from January of 2012.

††Annual rate of height decrease: Group 1 (<0.3 cm), Group 2 (0.3 to <0.6 cm), and Group 3 (≥0.6 cm).