Table 2.
Univariate | Multivariable | |||||
---|---|---|---|---|---|---|
OR | 95% CI | p | OR | 95% CI | p | |
Patient-associated factors | ||||||
Age | 1.02 | 0.998–1.04 | 0.085 | 1.00 | 0.97–1.02 | 0.83 |
Female sex | 2.84 | 1.13–7.15 | 0.027 | 2.45 | 0.86–6.99 | 0.095 |
Major comorbidity | 2.57 | 1.31–5.04 | 0.006 | 2.24 | 0.93–5.38 | 0.072 |
Cardiovascular | 3.12 | 1.56–6.25 | 0.001 | |||
Diabetes | 4.56 | 1.69–12.32 | 0.003 | |||
Pulmonary | 0.82 | 0.29–2.29 | 0.702 | |||
Antithrombotic agents | 3.33 | 1.34–8.27 | 0.010 | 1.94 | 0.61–6.17 | 0.264 |
Anticoagulant agents | 2.17 | 0.75–6.34 | 0.160 | |||
Antiplatelet agents | 5.31 | 1.09–25.95 | 0.039 | |||
SSRI or SNRI medication | 2.08 | 0.48–9.04 | 0.330 | |||
Chronic alcohol misuse | 0.91 | 0.46–1.81 | 0.790 | 1.41 | 0.63–3.15 | 0.404 |
Previous TBI | 1.00 | 0.40–2.48 | 0.995 | |||
Trauma-associated factors | ||||||
Primary GCS score | 0.94 | 0.85–1.03 | 0.188 | |||
Primary CT findings | ||||||
Intra-axial trauma lesions | 1.54 | 0.79–3.01 | 0.204 | |||
Midline shift | 2.03 | 1.03–4.01 | 0.042 | 2.26 | 1.05–4.84 | 0.036 |
Extracranial injuries | 3.14 | 1.31–7.54 | 0.010 | 4.71 | 1.74–12.73 | 0.002 |
Treatment-associated factors | ||||||
Major neurosurgical intervention | 5.69 | 2.75–11.78 | < 0.001 |
CI confidence interval, CT computed tomography, GCS Glasgow Coma Scale, OR odds ratio, SNRI serotonin and noradrenalin reuptake inhibitor, SSRI selective serotonin reuptake inhibitor, TBI traumatic brain injury