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. 2022 Jan 13;191(6):2759–2762. doi: 10.1007/s11845-021-02913-8

Table 2.

Absolute lymphocyte count and lymphocyte subsets before and after starting DMT. FTY but not DMF caused significant lymphopaenia. Treatment with FTY caused significant reductions in CD4 count but not CD8 count. DMF treatment did not significantly affect CD4 or CD8 count

Count Pre-DMT Post-DMT Paired t test two tailed significance
Mean SD Mean SD p value
FTY lymphocyte count (109/L) 1.60 0.34 0.34 0.05 0.001
DMF lymphocyte count (109/L) 2.58 1.47 2.28 1.12 0.683
Lymphocyte subsets
FTY CD4 (106/L) 780 184 57 87 0.002
DMF CD4 (106/L) 1028 506 671 507 0.069
FTY CD8 (106/L) 372 275 116 77 0.050
DMF CD8 (106/L) 603 425 394 465 0.100