Table 1.
Comparison of patient- and SAH-specific characteristics between early (< day 7) and late (≥ day 7) DCI onset
| DCI (n = 173) | Early DCI (n = 90) | Late DCI (n = 83) | p value | |
|---|---|---|---|---|
| Age (years), mean ± SD | 54.0 (12.7) | 52.5 ± 12.2 | 55.6 ± 13.1 | 0.106 |
| Sex (female/male), no. (%) | 124 (71.7)/49 (28.3) | 65 (72.2)/25 (27.8) | 59 (71.1)/24 (28.9) | 0.868 |
| Risk factors, no. (%) | ||||
| Hypertension | 69 (39.9) | 39 (43.3) | 30 (36.1) | 0.335 |
| Smoking | 59 (34.1) | 22 (24.4) | 37 (44.6) | 0.043 |
| Aneurysm location, no. (%) | 0.235 | |||
| Acomm | 60 (34.7) | 27 (30.0) | 33 (39.8) | |
| MCA | 49 (28.3) | 24 (26.7) | 25 (30.1) | |
| ICA | 27 (15.6) | 18 (20.0) | 9 (10.8) | |
| Others | 37 (21.4) | 21 (23.3) | 16 (19.3) | |
| Ant. circulation | 148 (85.5) | 78 (86.7) | 70 (84.3) | 0.663 |
| Post. circulation | 25 (14.5) | 12 (13.3) | 13 (15.7) | |
| Aneurysm size diameter maxium (mm), mean ± SD | 7.1 ± 3.7 | 6.9 ± 3.5 | 7.2 ± 4.0 | 0.574 |
| Hunt and Hess grade, no. (%) | 0.301 | |||
| Grade 1 | 19 (11.0) | 11 (12.2) | 8 (9.6) | |
| Grade 2 | 35 (20.2) | 14 (15.6) | 21 (25.3) | |
| Grade 3 | 56 (32.4) | 33 (36.7) | 23 (27.7) | |
| Grade 4 | 40 (23.1) | 18 (20.0) | 22 (26.5) | |
| Grade 5 | 23 (13.3) | 14 (15.6) | 9 (10.8) | |
| Intracerebral hemorrhage, no. (%) | 77 (44.5) | 39 (43.3) | 38 (45.8) | 0.746 |
| Acute hydrocephalus, no. (%) | 129 (74.6) | 65 (72.2) | 64 (77.1) | 0.461 |
| Modified Fisher scale, no. (%) | 0.269 | |||
| Grade 1 | 24 (13.9) | 10 (11.1) | 14 (16.9) | |
| Grade 2 | 17 (9.8) | 12 (13.3) | 5 (6.0) | |
| Grade 3 | 57 (32.9) | 32 (35.6) | 25 (30.1) | |
| Grade 4 | 74 (42.8) | 36 (40.0) | 39 (47.0) | |
| Aneurysm treatment, no. (%) | 0.976 | |||
| Clipping/endovascular | 79 (45.7)/94 (54.3) | 41 (45.6)/49 (54.4) | 38 (45.8)/45 (54.2) | |
| DCI surveillance | ||||
| INM, no. (%) | 0.735 | |||
| ptiO2 | 73 (42.2) | 39 (43.3) | 34 (41.0) | |
| CMD | 59 (34.1) | 30 (33.3) | 29 (34.9) | |
| Onset of first DCI event, days (IQR) | 6 (4–9) | 5 (3–5) | 9 (8–10) | < 0.001 |
Bold values indicate p < 0.05
Acomm Anterior communication aneurysm, CMD Cerebral microdialysis, DCI Delayed cerebral ischemia, ICA Internal carotid artery, INM Invasive neuromonitoring, IQR Interquartile range, MCA Middle cerebral artery, ptiO2 Brain tissue oxygen tension, SAH Subarachnoid hemorrhage