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. 2022 Nov 17;6:115. doi: 10.1186/s41687-022-00525-z

Table 2.

Factor loadings for factor analysis with oblique rotation

Factor
Item Question text 1 2 3 4 5
I-1 Do your toes begin to hurt when the ambient temperature or your body temperature rises? 0.799 − 0.125 − 0.004 − 0.047 0.052
I-6 Are you unable to perform your daily activities due to pain? 0.766 0.036 0.073 − 0.128 0.030
I-4 Do you feel pain in your knees when the ambient temperature or your body temperature rises? 0.729 − 0.059 − 0.135 − 0.190 0.290
I-7 Do your hands begin to hurt on cold days? 0.664 − 0.027 0.027 0.344 − 0.160
I-13 Do you experience any pain when your body temperature rises in the bath? 0.658 − 0.026 0.054 − 0.029 0.096
I-12 Are you immobile on hot days? 0.646 0.191 − 0.031 0.101 0.014
I-22 Do you have diarrhea? 0.585 0.192 0.010 0.028 − 0.194
I-9 Do your hands begin to hurt while using tap water? 0.448 − 0.018 0.052 0.376 − 0.056
I-24 Do you experience abdominal pain? 0.405 0.059 0.149 0.359 − 0.179
I-25 Do you feel nauseous? 0.396 0.006 0.197 0.270 0.029
V-8 Do you feel bitter because of prejudice toward Fabry disease at your workplace or school? − 0.129 0.807 0.199 0.032 − 0.099
V-9 Do people at your workplace or school ever make snide remarks about your Fabry disease symptoms? − 0.134 0.780 0.194 0.054 − 0.062
V-2 Does your Fabry disease treatment impact your work or schooling? 0.013 0.753 − 0.063 0.015 0.050
V-4 Do you feel that your hearing difficulty affects work or schooling? 0.079 0.729 − 0.126 0.195 − 0.057
V-3 Do you feel that working outside is difficult? 0.354 0.698 − 0.033 − 0.180 0.034
V-7 Do you get scolded by those around you because you become irritable due to pain from Fabry disease? 0.119 0.574 0.133 − 0.097 − 0.053
IV-5 Do you feel hurt because the people around you do n’t understand you? − 0.092 − 0.011 0.741 0.143 0.065
IV-6 Do you feel that you can’t properly explain Fabry disease symptoms to the people around you? − 0.007 0.082 0.635 0.102 − 0.040
III-1 Do you worry about your Fabry disease? 0.218 0.086 0.603 − 0.314 − 0.043
IV-2 Do you feel that playing or doing activities with friends is difficult because of the Fabry disease? 0.281 − 0.046 0.517 0.096 0.049
III-4 Do you feel anxious about your future because of the Fabry disease? 0.445 − 0.031 0.462 − 0.329 0.002
VI-6 Do you have trouble socializing with relatives due to the Fabry disease? − 0.212 0.348 0.462 − 0.045 0.045
I-33 Do you consider yourself mentally weak? 0.200 − 0.014 0.458 0.188 − 0.072
I-31 Do you get dizzy? 0.009 − 0.137 0.407 0.403 0.134
I-32 Do you feel you tire easily? 0.296 0.013 0.393 0.213 − 0.001
I-21 Do you have trouble socializing due to Fabry disease symptoms? 0.334 0.074 0.379 0.077 0.131
II-6 Are you concerned about side effects from your current treatment? − 0.251 0.245 0.313 0.197 0.267
I-26 Do you feel that lights are too bright? − 0.076 − 0.106 0.093 0.820 − 0.022
I-27 Do you have difficulty seeing at night? − 0.132 − 0.022 0.185 0.766 − 0.066
I-29 Do you feel that it is difficult to have conversations because of the ringing in your ears? 0.099 0.416 − 0.261 0.518 0.123
I-28 Do you hear ringing in your ears? 0.141 0.192 − 0.198 0.480 0.100
I-30 Do you experience sudden, intense ringing in your ears? 0.189 0.280 − 0.238 0.408 0.139
I-15 Do you feel pain in your chest or difficulty breathing while walking? 0.034 − 0.142 0.023 0.103 0.861
I-14 Do you experience palpitations? − 0.087 − 0.060 − 0.065 0.288 0.778
I-17 Do you feel anxious that your heart symptoms will get worse? 0.143 − 0.008 − 0.067 − 0.256 0.724
I-16 Do you feel pain in your chest or difficulty breathing while climbing stairs? 0.155 − 0.170 0.029 0.160 0.561
II-5 Are you anxious about the effectiveness of your current treatment? − 0.249 0.319 0.185 − 0.053 0.512
I-20 Do you feel anxious that your kidney symptoms will get worse? 0.059 0.234 0.163 − 0.328 0.504
I-18 Do your hands swell? 0.225 − 0.115 0.126 0.180 0.364

Factor extraction method: principal axis factoring; Rotation method: Promax with Kaiser normalization; The bold values are the factor loadings for the items included in each factor