Fig. 2.

Estimation of protein aggregates by ThT assay: ThT assay was performed to understand the unfolded protein aggregates in FCD patient samples (n = 26). The fluorescence intensity of ThT bound to protein aggregates was measured and shown as mean ± SEM. These results are representative of 3 independent experiments. Thioflavin T assay for focal cortical dysplasia (FCD) samples was performed based on clinical parameters; class 3 (P < 0.001) and class 2 (P < 0.03) showed a significant increase compared to ILAE class 1