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. 2022 Nov 4;13:1010044. doi: 10.3389/fgene.2022.1010044

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Copyright © 2022 Peng, Chi, Gao, Zhang, Song, Xie, Su, Song, Yang, Gu, Li, Xu, Li, Liu and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NFRGs risk score predicts tumor microenvironment and immune cell infiltration. (A) Immune cell bubble plots. (B) Immune cell and immune function ssGSEA scores between high and low-risk groups. (C) TME component analysis. (D) Immune checkpoint differences between high- and low-risk groups. (E) ICB response signature differences between high and low-risk groups. (F) Differences in immune steps with tumor between high- and low-risk groups. (G) Correlation between risk score and ICB response signature. (H) Correlation of risk scores with each step of the tumor immunization cycle. *p < 0.05; **p < 0.01; ***p < 0.001.