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. 2022 Nov 2;66:101628. doi: 10.1016/j.molmet.2022.101628

Table 1.

Summary of results for phase, amplitude, baseline and rhythmicity of core and accessory clock gene expression based on cosine regression analysis in the GI tract of Bmal1SCNfl/- mice and control. Bold p-values indicate significant difference between genotype.

Gastrointestinal tissue Gene Group Rhythmicity
Phase shift
Amplitude difference
Baseline difference
(P. value) (P. value) (P. value) (P. value)
Jejunum Bmal Bmal1SCN+/− 0.004 0.02 0.64 0.42
Bmal1SCNfl/- 0.01 Phase shift = 3.6
Per2 Bmal1SCN+/− 0.02 0.04 0.28 0.83
Bmal1SCNfl/- 0.01 Phase shift = 2.7
Rev-erbα Bmal1SCN+/− 0.03 0.03 0.28 0.04
Bmal1SCNfl/- 0.04 Phase shift = 5.7
Cry1 Bmal1SCN+/− 0.009 0.33 0.07 0.11
Bmal1SCNfl/- 0.42
Dbp Bmal1SCN+/− 0.056 0.08 0.08 0.14
Bmal1SCNfl/- 0.06
Cecum Bmal Bmal1SCN+/− 0.06 0.53 0.34 0.3
Bmal1SCNfl/- 0.33
Per2 Bmal1SCN+/− 0.00006 0.54 0.37 0.59
Bmal1SCNfl/- 0.31
Rev-erbα Bmal1SCN+/− 0.02 0.59 0.29 0.12
Bmal1SCNfl/- 0.08
Cry1 Bmal1SCN+/− 0.37 0.76 0.74 0.15
Bmal1SCNfl/- 0.52
Dbp Bmal1SCN+/− 0.056 0.78 0.34 0.45
Bmal1SCNfl/- 0.1
Proximal colon Bmal Bmal1SCN+/− 0.01 0.53 0.67 0.22
Bmal1SCNfl/- 0.04
Per2 Bmal1SCN+/− 0.004 0.56 0.13 0.25
Bmal1SCNfl/- 0.001
Rev-erbα Bmal1SCN+/− 0.03 0.98 0.02 0.07
Bmal1SCNfl/- 0.03
Cry1 Bmal1SCN+/− 0.01 0.27 0.94 0.47
Bmal1SCNfl/- 0.01
Dbp Bmal1SCN+/− 0.008 0.39 0.002 0.04
Bmal1SCNfl/- 0.07