| There has been an increased number of autoimmune diseases associated with acute COVID-19 infection. |
| Previous Epstein–Barr infection has been associated with a higher risk of developing multiple sclerosis. |
| Acute COVID-19 infection has been associated with a hyperinflammatory immune state, which could mask or trigger autoimmunity. |
| In this case series we describe a group of patients who developed multiple sclerosis and neuromyelitis optica spectrum disorder after acute COVID-19 infection. |
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