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IL-7 (multi-colored, colored with HDX uptake) complexed with IL-7Rα (green) models. Models were docked, clustered, then sorted into types by similarity. Models from each type are depicted in A-C, each utilizing two crosslinking restraints. D, the type 3 model with only one crosslinking restraint. Figure reproduced with permission from Zhang et al. (2019); copyright 2019 American Chemical Society.
